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Version 2014-12-22
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Details for endoplasmic reticulum unfolded protein response
Gene ontology ID
GO:0030968
Definition
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation
Comment
Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any response to the presence of unfolded proteins anywhere in the cell or in multicellular organism. Also see 'ER-associated protein catabolic process ; GO:0030433'.
Synonyms
1. ER unfolded protein response
2. erUPR
3. SREBP-mediated signalling pathway
References
1. GOC: mah
2. PMID 12042763
3. MIPS funcat: 32.01.07
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