Reference on EC 4.1.1.36 - phosphopantothenoylcysteine decarboxylase
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Brown, G.M.
The metabolism of pantothenic acid
J. Biol. Chem.
234
370-378
1959
Escherichia coli, Morganella morganii, Rattus norvegicus
Abiko, Y.
Investigations on pantothenic acid and its related compounds
J. Biochem.
61
300-308
1967
Rattus norvegicus
Scandurra, R.; Barboni, E.; Granata, F.; Pensa, B.; Costa, M.
Pantothenoylcysteine-4'-phosphate decarboxylase from horse liver
Eur. J. Biochem.
49
1-9
1974
Bos taurus, Oryctolagus cuniculus, Equus caballus, Rattus norvegicus, Sus scrofa
Abiko, Y.
Pantothenic acid and coenzyme A: phosphopantothenoylcysteine decarboxylase from rat liver [4'-phospho-N-(D-pantothenoyl)-L-cysteine carboxy-lyase, EC 4.1.1.36]
Methods Enzymol.
18
354-364
1970
Rattus norvegicus
-
Brohn, F.H.; Trager, W.
Coenzyme A requirement of malaria parasites: enzymes of coenzyme A biosynthesis in normal duck erythrocytes and erythrocytes infected with Plasmodium lophurae
Proc. Natl. Acad. Sci. USA
72
2456-2458
1975
Anas platyrhynchos, no activity in Plasmodium lophurae
Scandurra, R.; Moriggi, M.; Consalvi, V.; Politi, L.
Phosphopantothenoylcysteine decarboxylase from horse liver [4'-phospho-N-(D-pantothenoyl)-L-cysteine carboxy-lyase, EC 4.1.1.36]
Methods Enzymol.
62
245-248
1979
Equus caballus
Nishimura, N.; Kakimoto, T.; Chibata, I.
Mechanism of coenzyme A biosynthesis by Sarcina lutea
J. Ferment. Technol.
61
95-99
1983
Micrococcus luteus
-
Aberhart, D.J.; Ghoshal, P.K.; Cotting, J.A.; Russell, D.J.
Coenzyme A biosynthesis: Steric course of 4'-phosphopantothenoyl-L-cysteine decarboxylase
Biochemistry
24
7178-7182
1985
Rattus norvegicus
Scandurra, R.; Politi, L; Santoro, L.; Consalvi, V.
Covalently bound pyruvate in phosphopantothenoylcysteine decarboxylase from horse liver
FEBS Lett.
212
79-82
1987
Equus caballus
Yang, H.; Abeles, R.H.
Purification and properties of Escherichia coli 4'-phosphopantothenoylcysteine decarboxylase: presence of covalently bound pyruvate
Biochemistry
26
4076-4081
1987
Escherichia coli
Scandurra, R.; Consalvi, V.; Politi, L.; Gallina, C.
Functional residues at the active site of horse liver phosphopantothenoylcysteine decarboxylase
FEBS Lett.
231
192-196
1988
Equus caballus
Manoj, N.; Strauss, E.; Begley, T.P.; Ealick, S.E.
Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution
Structure
11
927-936
2003
Homo sapiens
Manoj, N.; Ealick, S.E.
Unusual space-group pseudosymmetry in crystals of human phosphopantothenoylcysteine decarboxylase
Acta Crystallogr. Sect. D
59
1762-1766
2003
Homo sapiens
Strauss, E.; Begley, T.P.
Stereochemical studies on phosphopantothenoylcysteine decarboxylase from Escherichia coli
Bioorg. Med. Chem. Lett.
13
339-342
2003
Escherichia coli
Strauss, E.; Begley, T.P.
Mechanistic studies on phosphopantothenoylcysteine decarboxylase
J. Am. Chem. Soc.
123
6449-6450
2001
Escherichia coli
Kupke, T.; Hernandez-Acosta, P.; Steinbacher, S.; Culianez-Macia, F.A.
Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis
J. Biol. Chem.
276
19190-19196
2001
Escherichia coli, Arabidopsis thaliana (Q9SWE5), Arabidopsis thaliana
Kupke, T.
Molecular characterization of the 4'-phosphopantothenoylcysteine decarboxylase domain of bacterial Dfp flavoproteins
J. Biol. Chem.
276
27597-27604
2001
Escherichia coli
Hernandez-Acosta, P.; Schmid, D.G.; Jung, G.; Culianez-Macia, F.A.; Kupke, T.
Molecular characterization of the Arabidopsis thaliana flavoprotein AtHAL3a reveals the general reaction mechanism of 4'-phosphopantothenoylcysteine decarboxylases
J. Biol. Chem.
277
20490-20498
2002
Arabidopsis thaliana
Steinbacher, S.; Hernandez-Acosta, P.; Bieseler, B.; Blaesse, M.; Huber, R.; Culianez-Macia, F.A.; Kupke, T.
Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate
J. Mol. Biol.
327
193-202
2003
Arabidopsis thaliana (Q9SWE5), Arabidopsis thaliana
Strauss, E.; Zhai, H.; Brand, L.A.; McLafferty, F.W.; Begley, T.P.
Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent
Biochemistry
43
15520-15533
2004
Homo sapiens
Yonamine, I.; Yoshida, K.; Kido, K.; Nakagawa, A.; Nakayama, H.; Shinmyo, A.
Overexpression of NtHAL3 genes confers increased levels of proline biosynthesis and the enhancement of salt tolerance in cultured tobacco cells
J. Exp. Bot.
55
387-395
2004
Nicotiana tabacum
Kupke, T.; Schwarz, W.
4-Phosphopantetheine biosynthesis in archaea
J. Biol. Chem.
281
5435-5444
2006
Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661
Kumar, P.; Chhibber, M.; Surolia, A.
How pantothenol intervenes in coenzyme-A biosynthesis of Mycobacterium tuberculosis
Biochem. Biophys. Res. Commun.
361
903-909
2007
Mycobacterium tuberculosis
Rubio, S.; Larson, T.R.; Gonzalez-Guzman, M.; Alejandro, S.; Graham, I.A.; Serrano, R.; Rodriguez, P.L.
An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment
Plant Physiol.
140
830-843
2006
Arabidopsis thaliana (Q9SWE5)
Zhang, N.; Wang, X.; Chen, J.
Role of OsHAL3 protein, a putative 4-phosphopantothenoylcysteine decarboxylase in rice
Biochemistry (Moscow)
74
61-67
2009
Oryza sativa
Sun, S.Y.; Chao, D.Y.; Li, X.M.; Shi, M.; Gao, J.P.; Zhu, M.Z.; Yang, H.Q.; Luan, S.; Lin, H.X.
OsHAL3 mediates a new pathway in the light-regulated growth of rice
Nat. Cell Biol.
11
845-851
2009
Oryza sativa
Ruiz, A.; Gonzalez, A.; Munoz, I.; Serrano, R.; Abrie, J.A.; Strauss, E.; Arino, J.
Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis
Nat. Chem. Biol.
5
920-928
2009
Saccharomyces cerevisiae
Afshar, N.; Argunhan, B.; Bettedi, L.; Szular, J.; Missirlis, F.
A recessive X-linked mutation causes a threefold reduction of total body zinc accumulation in Drosophila melanogaster laboratory strains
FEBS Open Bio
3
302-304
2013
Drosophila melanogaster
Petrenyi, K.; Molero, C.; Konya, Z.; Erdodi, F.; Arino, J.; Dombradi, V.
Analysis of two putative Candida albicans phosphopantothenoylcysteine decarboxylase / protein phosphatase Z regulatory subunits reveals an unexpected distribution of functional roles
PLoS ONE
11
e0160965
2016
Candida albicans (A0A1D8PKD2 and Q5A868), Candida albicans
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