show all | hide all No of entries

Information on EC 1.8.98.1 - dihydromethanophenazine:CoB-CoM heterodisulfide reductase

for references in articles please use BRENDA:EC1.8.98.1
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
This enzyme, found in methanogenic archaea that belong to the Methanosarcinales order, regenerates CoM and CoB after the action of EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase. It is a membrane-bound enzyme that contains (per heterodimeric unit) two distinct b-type hemes and two [4Fe-4S] clusters. cf. EC 1.8.7.3, ferredoxin:CoB-CoM heterodisulfide reductase, EC 1.8.98.5, H2:CoB-CoM heterodisulfide,ferredoxin reductase, EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase and EC 1.8.98.4, coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase.
Specify your search results
Select one or more organisms in this record: ?
Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
Co:CoM-S-S-CoB oxidoreductase system, CO:heterodisulfide oxidoreductase system, CoB-S-S-CoM reductase, Coenzyme B-Coenzyme M heterodisulfide reductase, coenzyme F420:heterodisulfide oxidoreductase, CoM-S-S-HTP reductase, DsrE2A, DsrK, F420H2-dependent CoM-S-S-HTP reductase, F420H2-dependent heterodisulfide reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CoB + CoM + methanophenazine = CoM-S-S-CoB + dihydromethanophenazine
show the reaction diagram
highly specific; This enzyme is found in methanogenic archaea, particularly Methanosarcina species, and regenerates coenzyme M and coenzyme B after the action of EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase. Contains (per heterodimeric unit) two distinct b-type hemes and two [4Fe-4S] clusters. Highly specific for both coenzyme M and coenzyme B. Reacts with various phenazine derivatives, including 2-hydroxyphenazine and 2-bromophenazine
-
-
-
Select items on the left to see more content.