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Literature summary for 1.8.98.1 extracted from
- A ferredoxin- and F420H2-dependent, electron-bifurcating, heterodisulfide reductase with homologs in the domains Bacteria and Archaea (2017), mBio, 8, e02285-16 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Methanosarcina acetivorans |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.1 | - |
coenzyme B | subunit HdrB2, at 21°C, pH not specified in the publication | Methanosarcina acetivorans |  |
| 1.2 | - |
coenzyme M | subunit HdrB2, at 21°C, pH not specified in the publication | Methanosarcina acetivorans | |
| 1.2 | - |
coenzyme B | subunit HdrB2C2, at 21°C, pH not specified in the publication | Methanosarcina acetivorans | |
| 1.4 | - |
coenzyme M | subunit HdrB2C2, at 21°C, pH not specified in the publication | Methanosarcina acetivorans | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | subunit HdrB2 contains zinc | Methanosarcina acetivorans | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methanosarcina acetivorans | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| coenzyme B + coenzyme M + reduced ferredoxin + H+ + coenzyme F420 | - |
Methanosarcina acetivorans | coenzyme B-coenzyme M disulfide + ferredoxin + H2 + reduced coenzyme F420 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 18000, subunit HdrC2, SDS-PAGE | Methanosarcina acetivorans |
| ? | x * 33000, subunit HdrB2, SDS-PAGE | Methanosarcina acetivorans |
| ? | x * 87000, subunit HdrA2, SDS-PAGE | Methanosarcina acetivorans |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Fdx:CoMS-SCoB oxidoreductase | - |
Methanosarcina acetivorans |
| ferredoxin- and F420H2-dependent, electron-bifurcating, heterodisulfide reductase | - |
Methanosarcina acetivorans |
| HDR | - |
Methanosarcina acetivorans |
| hdrA2B2C2 | - |
Methanosarcina acetivorans |
| heterodisulfide reductase | - |
Methanosarcina acetivorans |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| coenzyme F420 | - |
Methanosarcina acetivorans | |
| FAD | - |
Methanosarcina acetivorans | |
| [2Fe-2S]-center | - |
Methanosarcina acetivorans | |
| [4Fe-4S]-center | - |
Methanosarcina acetivorans | |
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Release 2023.1 (January 2023)
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