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A flavoprotein (FAD). The enzyme from human also has low activity with L-proline (cf. EC 220.127.116.11, proline dehydrogenase).
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The expected taxonomic range for this enzyme is: Tetrapoda
HPOX, hydroxyproline oxidase, HYPDH, OH-POX, ProDH2
, proline dehydrogenase 2, more
trans-4-hydroxy-L-proline + a quinone = (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + a quinol
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