EC Explorer
[browse EC tree] - [search]
EC 2.7.7.6 Details
EC number
2.7.7.6
Accepted name
DNA-directed RNA polymerase
Reaction
nucleoside triphosphate + RNAn = diphosphate + RNAn+1
Other name(s)
RNA polymerase,
RNA nucleotidyltransferase (DNA-directed),
RNA polymerase I,
RNA polymerase II,
RNA polymerase III,
C RNA formation factors,
deoxyribonucleic acid-dependent ribonucleic acid polymerase,
DNA-dependent ribonucleate nucleotidyltransferase,
DNA-dependent RNA nucleotidyltransferase,
DNA-dependent RNA polymerase,
ribonucleate nucleotidyltransferase,
ribonucleate polymerase,
C ribonucleic acid formation factors,
ribonucleic acid nucleotidyltransferase,
ribonucleic acid polymerase,
ribonucleic acid transcriptase,
ribonucleic polymerase,
ribonucleic transcriptase,
RNA nucleotidyltransferase,
RNA transcriptase,
transcriptase,
RNA nucleotidyltransferase I
Systematic name
nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed)
CAS registry number
9014-24-8
Comment
Catalyses DNA-template-directed extension of the 3′- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to α-amanitin, and the type of RNA synthesized. See also EC 2.7.7.19 (polynucleotide adenylyltransferase) and EC 2.7.7.48 (RNA-directed RNA polymerase).
History
created 1961, modified 1981, modified 1982, modified 1989
EC Tree
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_cross.png)
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_cross.png)
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_continue.png)
![](./taxonomy2/inc/tree/images/tree_cross.png)