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EC 1.13.11.54 Details
show Brenda entryEC number
1.13.11.54
Accepted name
acireductone dioxygenase [iron(II)-requiring]
Reaction
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-(methylsulfanyl)-2-oxobutanoate + formate
Other name(s)
ARD′,
2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous),
acireductone dioxygenase (ambiguous),
E-2′,
E-3 dioxygenase,
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)
Systematic name
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)
Comment
Requires iron(II). If Ni2+ is bound instead of iron(II), the reaction catalysed by EC 1.13.11.53, acireductone dioxygenase (Ni2+-requiring), occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway.
History
created 2006
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.6.2.1 created 1961, deleted 1965 1.6.2.3 created 1972, deleted 1965 1.6.99.4 created 1965, deleted 1972 1.6.99.8 created 1972, deleted 2002 1.6.99.9 created 1972, deleted 2002 1.6.99.10 created 1978, deleted 1981 1.6.99.11 created 1989, deleted 2002 1.6.99.12 created 1989, deleted 2002 1.6.99.13 created 1992, deleted 2002 1.13.11.21 created 1972, deleted 2001
