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EC 1.8.1.18 Details
show Brenda entryEC number
1.8.1.18
Accepted name
NAD(P)H sulfur oxidoreductase (CoA-dependent)
Reaction
hydrogen sulfide + NAD(P)+ = sulfur + NAD(P)H + H+
Other name(s)
NADPH NSR,
S0 reductase,
coenzyme A-dependent NADPH sulfur oxidoreductase
Systematic name
hydrogen sulfide:NAD(P)+ oxidoreductase (CoA-dependent)
Comment
This FAD-dependent enzyme, characterized from the archaeon Pyrococcus furiosus, is responsible for NAD(P)H-linked sulfur reduction. The activity with NADH is about half of that with NADPH. The reaction is dependent on CoA, although the nature of this dependency is not well understood.
History
created 2013
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.2.3.2 created 1961, deleted 1984 1.2.3.10 created 1990, deleted 2003 1.2.3.12 created 2000, deleted 2003 1.8.1.1 created 1961, deleted 1972
