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Information on EC 1.8.1.18 - NAD(P)H sulfur oxidoreductase (CoA-dependent)

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IUBMB Comments
This FAD-dependent enzyme, characterized from the archaeon Pyrococcus furiosus, is responsible for NAD(P)H-linked sulfur reduction. The activity with NADH is about half of that with NADPH. The reaction is dependent on CoA, although the nature of this dependency is not well understood.
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The enzyme appears in viruses and cellular organisms
Synonyms
CoA-dependent NAD(P)H: elemental sulfur (S0) oxidoreductase, coenzyme A-dependent NADPH sulfur oxidoreductase, NAD(P)H-dependent sulfur reductase, NAD(P)H: S0 oxidoreductase, NADPH NSR, NSR, PF1186, S(0) reductase, TK1186, TK1299, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
hydrogen sulfide + NAD(P)+ = sulfur + NAD(P)H + H+
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PATHWAY SOURCE
PATHWAYS
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