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EC 4.1.1.83 Details
EC number
4.1.1.83
Accepted name
4-hydroxyphenylacetate decarboxylase
Reaction
(4-hydroxyphenyl)acetate + H+ = 4-methylphenol + CO2
Other name(s)
p-hydroxyphenylacetate decarboxylase,
p-Hpd,
4-Hpd,
4-hydroxyphenylacetate carboxy-lyase
Systematic name
(4-hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming)
CAS registry number
340137-18-0
Comment
The enzyme, from the strict anaerobe Clostridium difficile, can also use (3,4-dihydroxyphenyl)acetate as a substrate, yielding 4-methylcatechol as a product. The enzyme is a glycyl radical enzyme.
History
created 2005
EC Tree
4.1.1.10 created 1961, deleted 1972
4.1.1.13 created 1961, deleted 1972
4.1.1.26 created 1961, deleted 1972
4.1.1.27 created 1961, deleted 1972