EC Explorer
[browse EC tree] - [search]
EC 4.1.1.72 Details
EC number
4.1.1.72
Accepted name
branched-chain-2-oxoacid decarboxylase
Reaction
(3S)-3-methyl-2-oxopentanoate = 2-methylbutanal + CO2
Other name(s)
branched-chain oxo acid decarboxylase,
branched-chain α-keto acid decarboxylase,
branched-chain keto acid decarboxylase,
BCKA,
(3S)-3-methyl-2-oxopentanoate carboxy-lyase
Systematic name
(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)
CAS registry number
63653-19-0
Comment
Acts on a number of 2-oxo acids, with a high affinity towards branched-chain substrates. The aldehyde formed may be enzyme-bound, and may be an intermediate in the bacterial system for the biosynthesis of branched-chain fatty acids.
History
created 1990
EC Tree
4.1.1.10 created 1961, deleted 1972
4.1.1.13 created 1961, deleted 1972
4.1.1.26 created 1961, deleted 1972
4.1.1.27 created 1961, deleted 1972