3.6.1.27: undecaprenyl-diphosphate phosphatase

This is an abbreviated version!
For detailed information about undecaprenyl-diphosphate phosphatase, go to the full flat file.

Word Map on EC 3.6.1.27

3.6.1.27

peptidoglycan

phosphatases

bacitracin

phosphatidic

vancomycin

cell-wall

phosphatidylglycerol

flippase

pyrophosphatases

undecaprenol

pharmacology

Reaction

ditrans,octacis-undecaprenyl diphosphate

Synonyms

bacA, BcrC, C55-isoprenyl diphosphatase, C55-isoprenyl pyrophosphatase, C55-PP phosphatase, C55-PP pyrophosphatase, Dolicholpyrophosphatase, HP0851, HupA, isoprenyl pyrophosphatase, More, PbrB, PgpB, SMU.244, Und-pp phosphatase, undecaprenyl diphosphate phosphatase, undecaprenyl pyrophosphatase, undecaprenyl pyrophosphate phosphatase, undecaprenyl-pyrophosphate phosphatase, UPP phosphatase, Upp-P, UPP-Pase, UppP, YbjG, YeiU

ECTree

3 Hydrolases

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.1.27 undecaprenyl-diphosphate phosphatase

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Results	in table
13	Activating Compound
47929	AA Sequence
1	Application
1	CAS Registry Number
9	Cloned(Commentary)
1	Crystallization (Commentary)
3	Expression
12	General Information
1	General Stability
51	IC50 Value
56	Inhibitors
1	Ki Value [mM]
12	KM Value [mM]
21	Localization
20	Metals/Ions
5	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
30	Organism
4	Pathway
7	PDB ID
6	pH Optimum
3	pH Range
1	pI Value
40	Protein Variants
9	Purification (Commentary)
1	Reaction
1	Reaction Type
26	Reference
1	Source Tissue
16	Specific Activity [micromol/min/mg]
61	Substrates and Products (Substrate)
9	Subunits
75	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
5	Temperature Stability [°C]
11	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.6.1.27 - undecaprenyl-diphosphate phosphatase

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0.0067

(5-bromo-2-[[3-(octyloxy)phenyl]methoxy]phenyl)phosphonic acid

2 entries

0.0065

2-(N-methyl-3-(octyloxy)benzamido)phenylphosphonic acid

Escherichia coli

at pH 7.5 and 20°C

756478

0.2

2-methoxy-6-[3-(octyloxy)benzamido]benzoic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.2

2-[3,4-bis(2-methoxyethoxy)benzamido]-5-bromobenzoic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.045

2-[3-(hexyloxy)benzamido]benzoic acid

2 entries

0.00083

2-[3-(octyloxy)benzamido]-5-(trifluoromethoxy)benzoic acid

2 entries

0.0042

2-[3-(octyloxy)benzamido]-5-phosphonobenzoic acid

2 entries

0.01

2-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.2

2-[methyl[3-(octyloxy)benzoyl]amino]benzoic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.2

3,4,5-trimethoxy-2-[3-(octyloxy)benzamido]benzoic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.0085

3-fluoro-2-[3-(octyloxy)benzamido]benzoic acid

Escherichia coli

at pH 7.5 and 20°C

756478

0.031

3-[3-(hexyloxy)benzamido]-4-hydroxybenzoic acid

Escherichia coli

pH and temperature not specified in the publication, mutant enzyme Y246D

756478

0.2

3-[3-(octyloxy)benzamido]benzene-1,2-dicarboxylic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.073

3-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.0034

4,5-difluoro-2-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.031

4-hydroxy-3-[3-(octyloxy)benzamido]benzoic acid

Escherichia coli

at pH 7.5 and 20°C

756478

0.2

4-[3-(octyloxy)benzamido]benzene-1,3-dicarboxylic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.0085 - 0.2

5-(diethoxyphosphoryl)-2-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.0098

5-(methanesulfonyl)-2-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.2

5-bromo-2-[3-(3,3-dimethylbut-1-yn-1-yl)benzamido]benzoic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.0042

5-bromo-2-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.003

5-chloro-2-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.0027

5-fluoro-2-(3-(octyloxy)benzamido)benzoic acid

Escherichia coli

at pH 7.5 and 20°C

756478

0.02

5-fluoro-2-[3-(hexyloxy)benzamido]benzoic acid

2 entries

0.0013 - 0.0027

5-fluoro-2-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.011

5-hydroxy-2-[3-(octyloxy)benzamido]benzoic acid

2 entries

0.2

5-methoxy-2-[3-(octyloxy)benzamido]benzoic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.2

5-methoxy-4-(2-methoxyethoxy)-2-[3-(octyloxy)benzamido]benzoic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.0013

5-nitro-2-[3-(octyloxy)benzamido]benzoic acid

Escherichia coli

at pH 7.5 and 20°C

756478

0.2

5-[3-(octyloxy)benzamido]benzene-1,3-dicarboxylic acid

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.032 - 0.033

bacitracin

3 entries

0.2

N-(2-carbamoylphenyl)-3-(octyloxy)benzamide

Escherichia coli

IC50 above 0.2 mM, at pH 7.5 and 20°C

756478

0.00003 - 0.0001

tripropeptin C

Micrococcus luteus

C5CBT8

in 100 mM Tris-HCl, 10 mM MgCl2 and 3.9 mM n-dodecyl-beta-maltoside (pH 7.5), 1.25 mM CaCl2, at 30°C

718588

0.0065

[2-[3-(octyloxy)benzamido]phenyl]phosphonic acid

Escherichia coli

pH and temperature not specified in the publication, mutant enzyme Y246D

756478

0.0071

[3-[3-(octyloxy)benzamido]phenyl]phosphonic acid

Escherichia coli

at pH 7.5 and 20°C

756478