3.6.1.27: undecaprenyl-diphosphate phosphatase

This is an abbreviated version!
For detailed information about undecaprenyl-diphosphate phosphatase, go to the full flat file.

Word Map on EC 3.6.1.27

Reaction

ditrans,octacis-undecaprenyl diphosphate
+
H2O
=
ditrans,octacis-undecaprenyl phosphate
+
phosphate

Synonyms

More, isoprenyl pyrophosphatase, C55-isoprenyl pyrophosphatase, C55-isoprenyl diphosphatase, Dolicholpyrophosphatase, undecaprenyl pyrophosphate phosphatase, BcrC, UppP, PgpB, undecaprenyl-pyrophosphate phosphatase, YbjG, YeiU, PbrB, C55-PP phosphatase, Und-pp phosphatase, Upp-P, bacA, UPP phosphatase, undecaprenyl pyrophosphatase, UPP-Pase, SMU.244, HupA, HP0851, C55-PP pyrophosphatase, undecaprenyl diphosphate phosphatase

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.27 undecaprenyl-diphosphate phosphatase

IC50 Value

IC50 Value on EC 3.6.1.27 - undecaprenyl-diphosphate phosphatase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0067
(5-bromo-2-[[3-(octyloxy)phenyl]methoxy]phenyl)phosphonic acid
0.0065
2-(N-methyl-3-(octyloxy)benzamido)phenylphosphonic acid
Escherichia coli
-
at pH 7.5 and 20°C
0.2
2-methoxy-6-[3-(octyloxy)benzamido]benzoic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.2
2-[3,4-bis(2-methoxyethoxy)benzamido]-5-bromobenzoic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.045
2-[3-(hexyloxy)benzamido]benzoic acid
0.00083
2-[3-(octyloxy)benzamido]-5-(trifluoromethoxy)benzoic acid
0.0042
2-[3-(octyloxy)benzamido]-5-phosphonobenzoic acid
0.01
2-[3-(octyloxy)benzamido]benzoic acid
0.2
2-[methyl[3-(octyloxy)benzoyl]amino]benzoic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.2
3,4,5-trimethoxy-2-[3-(octyloxy)benzamido]benzoic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.0085
3-fluoro-2-[3-(octyloxy)benzamido]benzoic acid
Escherichia coli
-
at pH 7.5 and 20°C
0.031
3-[3-(hexyloxy)benzamido]-4-hydroxybenzoic acid
Escherichia coli
-
pH and temperature not specified in the publication, mutant enzyme Y246D
0.2
3-[3-(octyloxy)benzamido]benzene-1,2-dicarboxylic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.073
3-[3-(octyloxy)benzamido]benzoic acid
0.0034
4,5-difluoro-2-[3-(octyloxy)benzamido]benzoic acid
0.031
4-hydroxy-3-[3-(octyloxy)benzamido]benzoic acid
Escherichia coli
-
at pH 7.5 and 20°C
0.2
4-[3-(octyloxy)benzamido]benzene-1,3-dicarboxylic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.0085 - 0.2
5-(diethoxyphosphoryl)-2-[3-(octyloxy)benzamido]benzoic acid
0.0098
5-(methanesulfonyl)-2-[3-(octyloxy)benzamido]benzoic acid
0.2
5-bromo-2-[3-(3,3-dimethylbut-1-yn-1-yl)benzamido]benzoic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.0042
5-bromo-2-[3-(octyloxy)benzamido]benzoic acid
0.003
5-chloro-2-[3-(octyloxy)benzamido]benzoic acid
0.0027
5-fluoro-2-(3-(octyloxy)benzamido)benzoic acid
Escherichia coli
-
at pH 7.5 and 20°C
0.02
5-fluoro-2-[3-(hexyloxy)benzamido]benzoic acid
0.0013 - 0.0027
5-fluoro-2-[3-(octyloxy)benzamido]benzoic acid
0.011
5-hydroxy-2-[3-(octyloxy)benzamido]benzoic acid
0.2
5-methoxy-2-[3-(octyloxy)benzamido]benzoic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.2
5-methoxy-4-(2-methoxyethoxy)-2-[3-(octyloxy)benzamido]benzoic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.0013
5-nitro-2-[3-(octyloxy)benzamido]benzoic acid
Escherichia coli
-
at pH 7.5 and 20°C
0.2
5-[3-(octyloxy)benzamido]benzene-1,3-dicarboxylic acid
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.032 - 0.033
bacitracin
0.2
N-(2-carbamoylphenyl)-3-(octyloxy)benzamide
Escherichia coli
-
IC50 above 0.2 mM, at pH 7.5 and 20°C
0.00003 - 0.0001
tripropeptin C
Micrococcus luteus
in 100 mM Tris-HCl, 10 mM MgCl2 and 3.9 mM n-dodecyl-beta-maltoside (pH 7.5), 1.25 mM CaCl2, at 30°C
0.0065
[2-[3-(octyloxy)benzamido]phenyl]phosphonic acid
Escherichia coli
-
pH and temperature not specified in the publication, mutant enzyme Y246D
0.0071
[3-[3-(octyloxy)benzamido]phenyl]phosphonic acid
Escherichia coli
-
at pH 7.5 and 20°C