3.6.1.27: undecaprenyl-diphosphate phosphatase
This is an abbreviated version!
For detailed information about undecaprenyl-diphosphate phosphatase, go to the full flat file.
Word Map on EC 3.6.1.27
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3.6.1.27
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peptidoglycan
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phosphatases
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bacitracin
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phosphatidic
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vancomycin
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cell-wall
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phosphatidylglycerol
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flippase
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pyrophosphatases
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undecaprenol
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pharmacology
- 3.6.1.27
- peptidoglycan
- phosphatases
- bacitracin
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phosphatidic
- vancomycin
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cell-wall
- phosphatidylglycerol
- flippase
- pyrophosphatases
- undecaprenol
- pharmacology
Reaction
Synonyms
bacA, BcrC, C55-isoprenyl diphosphatase, C55-isoprenyl pyrophosphatase, C55-PP phosphatase, C55-PP pyrophosphatase, Dolicholpyrophosphatase, HP0851, HupA, isoprenyl pyrophosphatase, More, PbrB, PgpB, SMU.244, Und-pp phosphatase, undecaprenyl diphosphate phosphatase, undecaprenyl pyrophosphatase, undecaprenyl pyrophosphate phosphatase, undecaprenyl-pyrophosphate phosphatase, UPP phosphatase, Upp-P, UPP-Pase, UppP, YbjG, YeiU
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Inhibitors
Inhibitors on EC 3.6.1.27 - undecaprenyl-diphosphate phosphatase
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2-[3-(octyloxy)benzamido]-5-(trifluoromethoxy)benzoic acid
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most potent inhibitor
tripropeptin C
tripropeptin C can potentially inhibit C55-PP phosphatase activity, which plays a crucial role in the lipid cycle of peptidoglycan synthesis
bacitracin
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complex formation with substrate + metal ion, reversed by addition of chelating agents
additional information
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the enzyme is not inhibited by Pb2+ (0.0001-10 mM)
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