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3.5.1.29: 2-(acetamidomethylene)succinate hydrolase

This is an abbreviated version!
For detailed information about 2-(acetamidomethylene)succinate hydrolase, go to the full flat file.

Word Map on EC 3.5.1.29

Reaction

2-(Acetamidomethylene)succinate
+ 2 H2O =
acetate
+
succinate semialdehyde
+
NH3
+
CO2

Synonyms

alpha-(N-acetylaminomethylene)succinic acid hydrolase, compound A hydrolase, alpha-(N-acetylaminomethylene)succinic acid amidohydrolase, AAMSAH, AAMS amidohydrolase, (E)-2-(acetamidomethylene)succinate hydrolase, E-2AMS hydrolase, mlr6787

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.29 2-(acetamidomethylene)succinate hydrolase

Inhibitors

Inhibitors on EC 3.5.1.29 - 2-(acetamidomethylene)succinate hydrolase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
alpha-hydroxyglutarate
-
competitive inhibition
alpha-ketoglutarate
citrate
-
competitive inhibition
diphosphate
fumarate
glutamate
-
competitive inhibition
Glutarate
-
competitive inhibition
Itaconate
malate
-
competitive inhibition
Maleate
-
competitive inhibition
malonate
-
competitive inhibition
N-acetyl-DL-aspartate
oxaloacetate
phosphate
SO32-
succinate
additional information
-
not inhibited by Zn2+, Fe2+, or Ni2+ (1 mM each), the enzyme is not affected when incubated for 30 min at 30°C in buffer containing 100 mM EDTA
-