3.5.1.29: 2-(acetamidomethylene)succinate hydrolase
This is an abbreviated version!
For detailed information about 2-(acetamidomethylene)succinate hydrolase, go to the full flat file.
Word Map on EC 3.5.1.29
-
3.5.1.29
-
semialdehyde
-
mesorhizobium
-
loti
-
pyridoxine
-
ammonia
-
dioxide
- 3.5.1.29
- semialdehyde
-
mesorhizobium
- loti
- pyridoxine
- ammonia
- dioxide
Reaction
Synonyms
(E)-2-(acetamidomethylene)succinate hydrolase, AAMS amidohydrolase, AAMSAH, alpha-(N-acetylaminomethylene)succinic acid amidohydrolase, alpha-(N-acetylaminomethylene)succinic acid hydrolase, compound A hydrolase, E-2AMS hydrolase, mlr6787
ECTree
Advanced search results
General Information
General Information on EC 3.5.1.29 - 2-(acetamidomethylene)succinate hydrolase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
metabolism
physiological function
binding of (E)-2-(acetamidomethylene)succinate to the enzyme is crucial for biological function of the enzyme and the last step reaction of vitamin B6 biological degradation
additional information
molecular docking of the two substrate isomers E- and Z-2-(acetamidomethylene)succinate to the hydrolase, molecular dynamics simulations and calculations of binding free energies, usage of X-ray crystal structure of E-2AMS hydrolase, PDB ID 3KXP, overview
AAMS amidohydrolase is involved in a degradation pathway of vitamin B6 (final step in degradation pathway I of vitamin B6)
metabolism
-
the enzyme catalyzes the final reaction in the degradation of vitamin B6
metabolism
binding of (E)-2-(acetamidomethylene)succinate to the enzyme is crucial for biological function of the enzyme and the last step reaction of vitamin B6 biological degradation