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3.1.3.3: phosphoserine phosphatase

This is an abbreviated version!
For detailed information about phosphoserine phosphatase, go to the full flat file.

Word Map on EC 3.1.3.3

Reaction

O-phospho-L(or D)-serine
+
H2O
=
L(or D)-serine
 +
phosphate

Synonyms

3-phosphoserine phosphatase, BSU04700, BSU04740, BSU34110, CTD phosphatase fcp1, HPSP, iPSP, iPSP1, iPSP2, L-phosphoserine phosphatase, metal-independent phosphoserine phosphatase, metal-independent PSP, More, O-phosphoserine phosphohydrolase, phosphatase, phosphoserine, phosphoserine phosphatase, phosphoserine phosphatase RsbP, phosphoserine phosphatase RsbU, phosphoserine phosphatase RsbX, phosphoserine:homoserine phosphotransferase, PP1, PSP, PSP1, pspA, PSPase, pspB, PSPH, RsbP, RsbU, RsbX, SerB, SerB PG0653, SerB2, SerB653, serine/threonine protein phosphatase, sigma-B negative effector, StP, THrH, TON_1161, yvfP

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.3 phosphoserine phosphatase

Inhibitors

Inhibitors on EC 3.1.3.3 - phosphoserine phosphatase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-(3-sulfopropyl)pyridin-1-ium
-
BeF3-
at 50°C, the hydrolytic activity of is markedly inhibited (more than 95%) in the presence of both BeCl2 and NaF. The latter is provided at concentrations that yield predominantly BeF3- in situ. Either BeCl2 or NaF alone has a much smaller inhibitory effect (35 or 20%, respectively). Similar inhibition by BeF3- is observed at room temperature or at 70°C
Cd2+
-
-
chlorpromazine
-
-
Clorobiocin
displays bactericidal activity and kills intracellular bacteria in a dose-dependent manner, highly specific in the ability to inhibit isoform SerB2 in comparison with human phosphoserine phosphatase
D-2-amino-3-phosphonopropionic acid
-
-
D-alanine
-
-
D-serine
DL-2-amino-3-phosphonopropionic acid
-
DL-2-Amino-4-phosphonobutyric acid
-
-
Glycerophosphorylcholine
-
-
glycine
hexadecylphosphocholine
-
-
iodoacetate
-
-
L-2-amino-3-phosphonopropionic acid
-
-
L-alanine
L-serine
N-ethylmaleimide
okadaic acid
-
-
p-chloromercuribenzoate
-
-
p-chloromercuriphenylsulfonate
-
-
phosphonoalanine
-
-
phosphorylcholine
-
-
rosaniline
displays bactericidal activity and kills intracellular bacteria in a dose-dependent manner
sodium orthovanadate
-
Trifluorperazine
-
-
vanadate
-
-
additional information
-