1.8.4.B3: thioredoxin-independent methionine sulfoxide reductases B

This is an abbreviated version!
For detailed information about thioredoxin-independent methionine sulfoxide reductases B, go to the full flat file.

Reaction

peptide-L-methionine-(R)-S-sulfoxide
+
thionein
=
peptide-L-methionine
+
thionein disulfide
+
H2O

Synonyms

hMsrB2, hMsrB3, NtMsrB1, thioredoxin-independent methionine sulfoxide reductases B

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.4 With a disulfide as acceptor
                1.8.4.B3 thioredoxin-independent methionine sulfoxide reductases B

Substrates Products

Substrates Products on EC 1.8.4.B3 - thioredoxin-independent methionine sulfoxide reductases B

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
dabsyl-L-methionine (R)-S-sulfoxide + bovine liver thionein
dabsyl-L-methionine + bovine liver thionein + H2O
show the reaction diagram
NtMsrB1
-
-
?
dabsyl-L-methionine (R)-S-sulfoxide + dithiothreitol
dabsyl-L-methionine + dithiothreitol disulfide + H2O
show the reaction diagram
NtMsrB1
-
-
?
dabsyl-L-methionine (R)-S-sulfoxide + plant Trx-like protein CDSP32
dabsyl-L-methionine + ?
show the reaction diagram
NtMsrB1
-
-
?
dabsyl-L-methionine (R)-S-sulfoxide + selenocysteamine
dabsyl-L-methionine + 2,2'-disulfanediyldiethanamine + H2O
show the reaction diagram
NtMsrB1
-
-
?
L-methionine (R)-S-sulfoxide + dithiothreitol
L-methionine + dithiothreitol disulfide + H2O
show the reaction diagram
-
-
-
?
L-methionine (R)-S-sulfoxide + thionein
L-methionine + thionein disulfide + H2O
show the reaction diagram
-
-
-
?
L-methionine (R)-S-sulfoxide + thioredoxin
L-methionine + thioredoxin disulfide
show the reaction diagram
reduced thioredoxin is not an efficient reducing agent for hMsrB3. Less than 5% of the activity with dithiothreitol
-
-
?
L-methionine (R)-S-sulfoxide + thioredoxin
L-methionine + thioredoxin disulfide + H2O
show the reaction diagram
reduced thioredoxin is not an efficient reducing agent for hMsrB2. Less than 5% of the activity with dithiothreitol
-
-
?
L-methionine (R)-sulfoxide + dithiothreitol
L-methionine + dithiothreitol disulfide
show the reaction diagram
-
-
-
?
peptide-L-methionine-(R)-S-sulfoxide + thionein
peptide-L-methionine + thionein disulfide + H2O
show the reaction diagram
-
-
-
?
additional information
?
-