1.3.99.41: 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase

This is an abbreviated version!
For detailed information about 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase, go to the full flat file.

Reaction

Synonyms

3-methylmercaptopropionyl coenzyme A dehydrogenase, 3-methylmercaptopropionyl-CoA dehydrogenase, dmdC, DmdC1, MMPA-CoA dehydrogeanase, MMPA-CoA dehydrogenase, SAR11_0249, SL157_0694, SPO3804

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.99 With unknown physiological acceptors

                1.3.99.41 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
2	Expression
2	General Information
1	Inhibitors
21	KM Value [mM]
1	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
6	Organism
3	Pathway
1	pH Optimum
1	pH Range
12	Protein Variants
1	Reaction
6	Reference
3	Specific Activity [micromol/min/mg]
14	Substrates and Products (Substrate)
2	Subunits
17	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]

Substrates Products

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Substrates Products on EC 1.3.99.41 - 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

3-(methylsulfanyl)propanoyl-CoA + acceptor

3-(methylsulfanyl)acryloyl-CoA + reduced acceptor

2 entries

3-(methylsulfanyl)propanoyl-CoA + FAD

3-(methylsulfanyl)acryloyl-CoA + FADH2

3 entries

3-(methylthio)propionyl-CoA + acceptor

(2E)-3-(methylthio)prop-2-enoyl-CoA + reduced acceptor

2 entries

butyryl-CoA + acceptor

?

Ruegeria pomeroyi

-

-

763984

-

-

?

caproyl-CoA + acceptor

?

Ruegeria pomeroyi

-

-

763984

-

-

?

caprylyl-CoA + acceptor

?

Ruegeria pomeroyi

-

-

763984

-

-

?

heptanoyl-CoA + acceptor

?

Ruegeria pomeroyi

-

-

763984

-

-

?

isobutyryl-CoA + acceptor

?

Ruegeria pomeroyi

-

-

763984

-

-

?

valeryl-CoA + acceptor

?

Ruegeria pomeroyi

-

-

763984

-

-

?

3-(methylsulfanyl)propanoyl-CoA + acceptor

3-(methylsulfanyl)acryloyl-CoA + reduced acceptor

Ruegeria pomeroyi

-

-

763984

-

-

?

3-(methylsulfanyl)propanoyl-CoA + acceptor

3-(methylsulfanyl)acryloyl-CoA + reduced acceptor

Ruegeria pomeroyi

-

best substrate

763984

-

-

?

3-(methylsulfanyl)propanoyl-CoA + FAD

3-(methylsulfanyl)acryloyl-CoA + FADH2

Roseovarius nubinhibens

A3SI50

-

765397

-

-

?

3-(methylsulfanyl)propanoyl-CoA + FAD

3-(methylsulfanyl)acryloyl-CoA + FADH2

Ruegeria lacuscaerulensis

-

-

765467

-

-

?

3-(methylsulfanyl)propanoyl-CoA + FAD

3-(methylsulfanyl)acryloyl-CoA + FADH2

Ruegeria pomeroyi

-

-

764751, 765467

-

-

?

3-(methylthio)propionyl-CoA + acceptor

(2E)-3-(methylthio)prop-2-enoyl-CoA + reduced acceptor

Ruegeria pomeroyi

Q5LLW7

-

728373

-

-

?

3-(methylthio)propionyl-CoA + acceptor

(2E)-3-(methylthio)prop-2-enoyl-CoA + reduced acceptor

Ruegeria pomeroyi

Q5LLW7

once released from phytoplankton, marine bacteria degrade dimethylsulfoniopropionate by either the cleavage pathway (to form the volatile gas dimethylsulfide) or the demethylation pathway (yielding methanethiol, which is readily assimilated or oxidized). The enzyme DmdC, 3-(methylthio)propionyl-CoA dehydrogenase, catalyzes the first step in the demethylation pathway

728373

-

-

?