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1.3.99.41: 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase

This is an abbreviated version!
For detailed information about 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase, go to the full flat file.

Reaction

3-(methylsulfanyl)propanoyl-CoA
+
acceptor
=
3-(methylsulfanyl)acryloyl-CoA
+
reduced acceptor

Synonyms

3-methylmercaptopropionyl coenzyme A dehydrogenase, 3-methylmercaptopropionyl-CoA dehydrogenase, dmdC, DmdC1, MMPA-CoA dehydrogeanase, MMPA-CoA dehydrogenase, SAR11_0249, SL157_0694, SPO3804

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.99 With unknown physiological acceptors
                1.3.99.41 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase

Expression

Expression on EC 1.3.99.41 - 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
the amount of transcripts for dmdB, dmdC and dmdD increases during growth of wild-type enzyme on methylmercaptopropionate or 3-(dimethylsulphonio)propanoate, as expected if the pathway is required for 3-(methylthio)propanoate metabolism. Following growth with 3-(dimethylsulphonio)propanoate, the levels of DmdC and DmdD activity in the deletion mutant dmdC are greatly reduced
the enzyme is up-regulated by dimethylsulfoniopropionate