1.2.1.15: malonate-semialdehyde dehydrogenase

This is an abbreviated version!
For detailed information about malonate-semialdehyde dehydrogenase, go to the full flat file.

Reaction

3-oxopropanoate
+
NAD(P)+
+
H2O
=
malonate
+
NAD(P)H
+ 2 H+

Synonyms

dehydrogenase, malonate semialdehyde, IolA, KES23460, NAD-dependent malonate-semialdehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.15 malonate-semialdehyde dehydrogenase

Substrates Products

Substrates Products on EC 1.2.1.15 - malonate-semialdehyde dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-oxopropanoate + NAD+ + H2O
malonate + NADH
show the reaction diagram
-
-
-
-
-
malonic semialdehyde + NAD+
acetyl-CoA + NADH + CO2
show the reaction diagram
-
-
-
-
?
NAD(P)+ + 3-oxopropanoate + H2O
malonate + NAD(P)H
show the reaction diagram
-
-
-
ir
additional information
?
-
-
no activity with formaldehyde, acetaldehyde, propionaldehyde, isovaleraldehyde, benzaldehyde, anisaldehyde, glyceraldehyde, glyceraldehyde-3-phosphate, glyoxylate, succinic semialdehyde
-
-
-