1.2.1.15: malonate-semialdehyde dehydrogenase

This is an abbreviated version!
For detailed information about malonate-semialdehyde dehydrogenase, go to the full flat file.

Reaction

3-oxopropanoate
+
NAD(P)+
+
H2O
=
malonate
+
NAD(P)H
+ 2 H+

Synonyms

dehydrogenase, malonate semialdehyde, IolA, KES23460, NAD-dependent malonate-semialdehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.15 malonate-semialdehyde dehydrogenase

Purification

Purification on EC 1.2.1.15 - malonate-semialdehyde dehydrogenase

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant enzyme from Escherichia coli strain BL21(DE3) by nickel affinity chromatography, gel filtration, and ultrafiltration to over 95% purity