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1.14.20.4: anthocyanidin synthase

This is an abbreviated version!
For detailed information about anthocyanidin synthase, go to the full flat file.

Word Map on EC 1.14.20.4

Reaction

a (2R,3S,4S)-leucoanthocyanidin
+
2-oxoglutarate
+
O2
=
a (4S)- 2,3-dehydroflavan-3,4-diol
+
succinate
+
CO2
+
H2O

Synonyms

ANS, ANS-1, ANS-2, anthocyanidin synthase, anthocyanidin synthase 1, anthocyanidine synthase, anthocyanin synthase, FcANS1, GbANS, IbANS, LDOX, leucoanthocyanidin dioxygenase, leucoanthocyanidin oxygenase, leucocyanidin dioxygenase, leucocyanidin oxygenase, leucocyanidin,2-oxoglutarate:oxygen oxidoreductase, McANS-1, McANS-2, MdANS, RtLDOX

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
                1.14.20.4 anthocyanidin synthase

Natural Substrates Products

Natural Substrates Products on EC 1.14.20.4 - anthocyanidin synthase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2R,3S,4S-cis-leucoanthocyanidin + 2-oxoglutarate + O2
cis- and trans-dihydroquercetins + succinate + CO2 + 2 H2O
show the reaction diagram
-
catalyses the penultimate step in anthocyanin biosynthesis by oxidation of the 2R,3S,4S-cis-leucoanthocyanidins
both quercetin and dihydroquercetin are products with the distribution being dependent on the C-4 stereochemistry of the leucocyanidin substrates
-
?
additional information
?
-