1.14.14.55: quinine 3-monooxygenase

This is an abbreviated version, for detailed information about quinine 3-monooxygenase, go to the full flat file.

Reaction

Quinine
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
3-hydroxyquinine
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP2C19, CYP3A, CYP3A4, CYPIIIA4, cytochrome P450 isoform, NF-25, Nifedipine oxidase, P450-PCN1, quinine 3-hydroxylase, Quinine 3-monooxygenase, quinine monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.55 quinine 3-monooxygenase