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1.14.14.55: quinine 3-monooxygenase

This is an abbreviated version!
For detailed information about quinine 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.55

Reaction

Quinine
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
3-hydroxyquinine
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP2C19, CYP3A, CYP3A4, CYPIIIA4, cytochrome P450 isoform, EC 1.14.13.67, NF-25, Nifedipine oxidase, P450-PCN1, quinine 3-hydroxylase, Quinine 3-monooxygenase, quinine monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.55 quinine 3-monooxygenase

Cloned

Cloned on EC 1.14.14.55 - quinine 3-monooxygenase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression of CYP3A4 in human B lymphoblastoid cell line AHH-1
-
genes CYP3A5 and CYP3A4, DNA sequence determination, genotyping of two different human populations revealing the CYP3A5 and the CYP3A4 genotypes
-