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1.14.14.55: quinine 3-monooxygenase

This is an abbreviated version!
For detailed information about quinine 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.55

Reaction

Quinine
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
3-hydroxyquinine
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP2C19, CYP3A, CYP3A4, CYPIIIA4, cytochrome P450 isoform, EC 1.14.13.67, NF-25, Nifedipine oxidase, P450-PCN1, quinine 3-hydroxylase, Quinine 3-monooxygenase, quinine monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.55 quinine 3-monooxygenase

Sequence

Sequence on EC 1.14.14.55 - quinine 3-monooxygenase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CP3A4_HUMAN
503
2
57343
Swiss-Prot
Secretory Pathway (Reliability: 1)
B7P714_IXOSC
163
0
18794
TrEMBL
other Location (Reliability: 3)
B7PME9_IXOSC
524
2
60217
TrEMBL
Secretory Pathway (Reliability: 2)
B7P1N3_IXOSC
259
1
29542
TrEMBL
Secretory Pathway (Reliability: 1)
B7PKJ0_IXOSC
159
0
18245
TrEMBL
other Location (Reliability: 2)
B7PVW7_IXOSC
508
2
58183
TrEMBL
Secretory Pathway (Reliability: 1)
B7Q1D1_IXOSC
140
0
16124
TrEMBL
Secretory Pathway (Reliability: 4)
B7PVW8_IXOSC
419
0
47479
TrEMBL
other Location (Reliability: 2)
B7Q2U5_IXOSC
498
1
57077
TrEMBL
Secretory Pathway (Reliability: 2)
B7P2B0_IXOSC
208
1
24239
TrEMBL
Mitochondrion (Reliability: 5)
B7PES7_IXOSC
363
0
41726
TrEMBL
Mitochondrion (Reliability: 2)
B7P5J6_IXOSC
278
0
31788
TrEMBL
other Location (Reliability: 3)
B7PSW1_IXOSC
280
1
31440
TrEMBL
other Location (Reliability: 2)
B7PWV9_IXOSC
146
1
16730
TrEMBL
Secretory Pathway (Reliability: 1)
B7PFG4_IXOSC
180
0
20790
TrEMBL
other Location (Reliability: 3)
B7P1N5_IXOSC
189
0
21341
TrEMBL
Mitochondrion (Reliability: 5)
B7Q3W6_IXOSC
135
0
15185
TrEMBL
other Location (Reliability: 2)
B7P0T0_IXOSC
202
1
23253
TrEMBL
Mitochondrion (Reliability: 5)
B7QD99_IXOSC
209
1
24137
TrEMBL
Secretory Pathway (Reliability: 4)
B7QDA0_IXOSC
504
1
57487
TrEMBL
Secretory Pathway (Reliability: 3)
E0VSD4_PEDHC
529
0
61663
TrEMBL
Secretory Pathway (Reliability: 2)
B7P474_IXOSC
185
0
21199
TrEMBL
other Location (Reliability: 3)
B7P0T1_IXOSC
178
0
20949
TrEMBL
Mitochondrion (Reliability: 4)
B7QJP4_IXOSC
135
0
15355
TrEMBL
other Location (Reliability: 2)
B7P2B2_IXOSC
204
2
23463
TrEMBL
Secretory Pathway (Reliability: 2)
CP3A4_HUMAN
503
2
57343
Swiss-Prot
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