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1.14.13.239: carnitine monooxygenase

This is an abbreviated version!
For detailed information about carnitine monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.239

Reaction

L-carnitine
+
NAD(P)H
+
H+
+
O2
=
(3R)-3-hydroxy-4-oxobutanoate
+
trimethylamine
+
NAD(P)+
+
H2O

Synonyms

carnitine TMA lyase, CntA, cntAB, CntB, yeaWX

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.239 carnitine monooxygenase

IC50 Value

IC50 Value on EC 1.14.13.239 - carnitine monooxygenase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0011
6-(5-bromopyridin-3-yl)-N-[3-(1H-imidazol-1-yl)propyl]-2-phenylpyrimidin-4-amine
Acinetobacter baumannii
pH 7.6, temperature not specified in the publication
-
0.0058
N-[(oxan-4-yl)methyl]-5-(thiophen-2-yl)imidazo[2,1-b][1,3,4]thiadiazol-2-amine
Acinetobacter baumannii
pH 7.6, temperature not specified in the publication
-
0.0049
N-[3-(1H-imidazol-1-yl)propyl]-8-methyl-1,6-naphthyridine-2-carboxamide
Acinetobacter baumannii
pH 7.6, temperature not specified in the publication
-