1.14.13.166: 4-nitrocatechol 4-monooxygenase

This is an abbreviated version!
For detailed information about 4-nitrocatechol 4-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.166

Reaction

4-nitrocatechol
+
NAD(P)H
+
H+
+
O2
=
2-hydroxy-1,4-benzoquinone
+
nitrite
+
NAD(P)+
+
H2O

Synonyms

4-nitrophenol 4-monooxygenase/4-nitrocatechol 2-monooxygenase, NpcA, npcB, NpdA2, p-nitrophenol monooxygenase, p-nitrophenol monooxygenase-II, para-nitrophenol 4-monooxygenase, PdcA, pentachlorophenol-4-monooxygenase, PNP 4-monooxygenase, PNP monooxygenase, pnpA, two-component PNP monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.166 4-nitrocatechol 4-monooxygenase

Inhibitors

Inhibitors on EC 1.14.13.166 - 4-nitrocatechol 4-monooxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
-
Methimazole
-
58% inhibition at 0.5 mM
additional information
-
alpha-naphthoflavone, miconazole, and metyrapone at 0.5 mM have very little effect (less than 5% inhibition) on enzyme activity
-