1.14.13.166: 4-nitrocatechol 4-monooxygenase

This is an abbreviated version!
For detailed information about 4-nitrocatechol 4-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.166

Reaction

4-nitrocatechol
+
NAD(P)H
+
H+
+
O2
=
2-hydroxy-1,4-benzoquinone
+
nitrite
+
NAD(P)+
+
H2O

Synonyms

4-nitrophenol 4-monooxygenase/4-nitrocatechol 2-monooxygenase, NpcA, npcB, NpdA2, p-nitrophenol monooxygenase, p-nitrophenol monooxygenase-II, para-nitrophenol 4-monooxygenase, PdcA, pentachlorophenol-4-monooxygenase, PNP 4-monooxygenase, PNP monooxygenase, pnpA, two-component PNP monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.166 4-nitrocatechol 4-monooxygenase

Systematic Name

Systematic Name on EC 1.14.13.166 - 4-nitrocatechol 4-monooxygenase

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SYSTEMATIC NAME
IUBMB Comments
4-nitrocatechol,NAD(P)H:oxygen 4-oxidoreductase (4-hydroxylating, nitrite-forming)
Contains FAD. The enzyme catalyses the oxidation of 4-nitrocatechol with the concomitant removal of the nitro group as nitrite. Forms a two-component system with a flavoprotein reductase [1]. The enzymes from the bacteria Lysinibacillus sphaericus JS905 and Rhodococcus sp. strain PN1 were shown to also catalyse EC 1.14.13.29, 4-nitrophenol 2-monooxygenase [1,2] while the enzyme from Pseudomonas sp. WBC-3 was shown to also catalyse EC 1.14.13.167, 4-nitrophenol 4-monooxygenase [3].