1.11.2.6: L-tyrosine peroxygenase

This is an abbreviated version!
For detailed information about L-tyrosine peroxygenase, go to the full flat file.

Word Map on EC 1.11.2.6

Reaction

L-tyrosine
+
H2O2
=
L-Dopa
+
H2O

Synonyms

L-tyrosine 3-hydroxylase, LmbB2, Orf13, TyrH

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.2 Peroxygenases
                1.11.2.6 L-tyrosine peroxygenase

Substrates Products

Substrates Products on EC 1.11.2.6 - L-tyrosine peroxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-(4-hydroxylphenyl)propanoic acid + H2O2
3-(3,4-hydroxyphenyl) propanoic acid + H2O
show the reaction diagram
-
-
-
0
?
3-chloro-L-tyrosine + H2O2
3-chloro-5-hydroxyl-L-tyrosine + L-dopa + Cl-
show the reaction diagram
-
the enzyme performs oxidative C-H bond cleavage at C5 to generate 3-chloro-5-hydroxyl-L-tyrosine and oxygenation at C3 concomitant with a carbon-fluorine bond cleavage to yield L-dopa and chloride
-
0
?
3-fluoro-L-tyrosine + H2O2
3-fluoro-5-hydroxyl-L-tyrosine + L-dopa + F-
show the reaction diagram
-
the enzyme performs oxidative C-H bond cleavage at C5 to generate 3-fluoro-5-hydroxyl-L-tyrosine and oxygenation at C3 concomitant with a carbon-fluorine bond cleavage to yield L-dopa and fluoride
-
0
?
3-iodo-L-tyrosine + H2O2
3-iodo-5-hydroxyl-L-tyrosine + L-dopa + I-
show the reaction diagram
-
the enzyme performs oxidative C-H bond cleavage at C5 to generate 3-iodo-5-hydroxyl-L-tyrosine and oxygenation at C3 concomitant with a carbon-fluorine bond cleavage to yield L-dopa and iodide
-
0
?
3-nitro-L-tyrosine + H2O2
3-nitro-5-hydroxyl-L-tyrosine + H2O
show the reaction diagram
-
-
-
0
?
4-cresol + H2O2
4-methylcatechol + H2O
show the reaction diagram
-
-
-
0
?
DL-tyrosine + H2O2
L-DOPA + H2O
show the reaction diagram
-
-
-
0
?
L-tyrosine + H2O2
L-dopa + H2O
show the reaction diagram
tyramine + H2O2
dopamine + H2O
show the reaction diagram
-
-
-
0
?
additional information
?
-