Literature summary for 1.11.2.6 extracted from

Neusser, D.; Schmidt, H.; Spizek, J.; Novotna, J.; Peschke, U.; Kaschabeck, S.; Tichy, P.; Piepersberg, W.
The genes ImbB1 and ImbB2 of Streptomyces lincolnensis encode enzymes involved in the conversion of L-tyrosine to propylproline during the biosynthesis of the antibiotic lincomycin A (1998), Arch. Microbiol., 169, 322-332 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21 (DE3) cells	Streptomyces lincolnensis

Inhibitors

Inhibitors	Comment	Organism	Structure
H2O2	-	Streptomyces lincolnensis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-tyrosine + H2O2	Streptomyces lincolnensis	-	L-dopa + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces lincolnensis	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-NTA column chromatography	Streptomyces lincolnensis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-tyrosine + H2O2	-	Streptomyces lincolnensis	L-dopa + H2O	-	?

Subunits

Subunits	Comment	Organism
?	x * 38000, SDS-PAGE	Streptomyces lincolnensis

Synonyms

Synonyms	Comment	Organism
L-tyrosine 3-hydroxylase	-	Streptomyces lincolnensis
LmbB2	-	Streptomyces lincolnensis

Cofactor

Cofactor	Comment	Organism	Structure
heme b	-	Streptomyces lincolnensis

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Release 2023.1 (January 2023)