1.1.99.30: 2-oxo-acid reductase

This is an abbreviated version!
For detailed information about 2-oxo-acid reductase, go to the full flat file.

Reaction

a (2R)-hydroxy-carboxylate
+
acceptor
=
a 2-oxo-carboxylate
+
reduced acceptor

Synonyms

(2R)-hydroxycarboxlate viologen oxidoreductase, (2R)-hydroxycarboxlate-viologen-oxidoreductase, (2R)-hydroxycarboxylate-viologen-oxidoreductase, 2-oxoacid reductase, D-2-hydroxy acid dehydrogenase, dehydrogenase, D-2-hydroxy acid, HVOR, hydroxy carboxylate viologen oxidoreductase, hydroxycarboxlate-oxidoreductase, hydroxycarboxlate-viologen-oxidoreductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.30 2-oxo-acid reductase

Substrates Products

Substrates Products on EC 1.1.99.30 - 2-oxo-acid reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2R)-hydroxy-4-methylpentanoate + 2-oxo-butyrate
2-oxo-4-methylpentanoate + (2R)-hydroxybutyrate
show the reaction diagram
-
-
-
0
r
(2S,3R,4S)-2-hydroxy-3-halogenbutyrolactones + reduced benzyl viologen
?
show the reaction diagram
-
highly stereospecific reaction
-
0
r
(2S,3R,4S)-2-hydroxy-3-halogenbutyrolactones + reduced methyl viologen
?
show the reaction diagram
-
highly stereospecific reaction
-
0
r
(R)-lactate + oxidized anthraquinone-2,6-disulfonate
pyruvate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
?
(R,S)-2-oxo-3-methylpentanoate + reduced benzyl viologen
2-hydroxy-3-methylpentanoate + oxidized benzyl viologen
show the reaction diagram
-
-
-
0
?
(R,S)-2-oxo-3-methylpentanoate + reduced methyl viologen
2-hydroxy-3-methylpentanoate + oxidized methyl viologen
show the reaction diagram
-
-
-
0
?
(S)-2-oxo-3-methylpentanoate + reduced benzyl viologen
2-hydroxy-3-methylpentanoate + oxidized benzyl viologen
show the reaction diagram
(S)-2-oxo-3-methylpentanoate + reduced methyl viologen
2-hydroxy-3-methylpentanoate + oxidized methyl viologen
show the reaction diagram
2-hydroxyglutarate + oxidized acceptor
2-oxoglutarate + reduced acceptor
show the reaction diagram
-
-
-
0
r
2-oxo-3,3-dimethyl-4-hydroxybutanoate + reduced benzyl viologen
3,3-dimethyl-2,4-dihydroxybutanoate + oxidized benzyl viologen
show the reaction diagram
2-oxo-3,3-dimethyl-4-hydroxybutanoate + reduced methyl viologen
3,3-dimethyl-2,4-dihydroxybutanoate + oxidized methyl viologen
show the reaction diagram
2-oxo-3,5-dienoates + H2
?
show the reaction diagram
-
-
-
0
r
2-oxo-3-(3,4-dihydroxyphenyl)-propionate + H2
rosmarinic acid
show the reaction diagram
-
-
-
0
r
2-oxo-3-enoates + H2
?
show the reaction diagram
-
-
-
0
r
2-oxo-4-(hydroxy-methyl-phosphinyl)-butanoate + reduced benzyl viologen
2-hydroxy-4-(hydroxymethylphosphinyl)-butanoate + oxidized benzyl viologen
show the reaction diagram
-
-
-
0
?
2-oxo-4-(hydroxy-methyl-phosphinyl)-butanoate + reduced methyl viologen
2-hydroxy-4-(hydroxymethylphosphinyl)-butanoate + oxidized methyl viologen
show the reaction diagram
-
-
-
0
?
2-oxo-4-methylpentanoate + reduced benzyl viologen
2-hydroxy-4-methylpentanoate + oxidized benzyl viologen
show the reaction diagram
-
-
-
0
?
2-oxo-4-methylpentanoate + reduced methyl viologen
2-hydroxy-4-methylpentanoate + oxidized methyl viologen
show the reaction diagram
-
-
-
0
?
2-oxo-carboxylate + reduced benzyl viologen
(2R)-hydroxy-carboxylate + oxidized benzyl viologen
show the reaction diagram
-
stereospecific, very wide substrate specificity, reduces 2-oxo-carboxylates with diverse types of residues at position 3, such as unbranched and branched alkyl, hydroxy, one or two conjugated carbon carbon double bonds, additional CO, and -OOC(CH2)n, overview
-
0
r
2-oxo-carboxylate + reduced methyl viologen
(2R)-hydroxy-carboxylate + oxidized methyl viologen
show the reaction diagram
-
stereospecific, very wide substrate specificity, reduces 2-oxo-carboxylates with diverse types of residues at position 3, such as unbranched and branched alkyl, hydroxy, one or two conjugated carbon carbon double bonds, additional CO, and -OOC(CH2)n, overview
-
0
r
2-oxoadipate + reduced benzyl viologen
2-hydroxyadipate + oxidized benzyl viologen
show the reaction diagram
-
-
-
0
?
2-oxoadipate + reduced methyl viologen
2-hydroxyadipate + oxidized methyl viologen
show the reaction diagram
-
-
-
0
?
2-oxoglutarate + reduced benzyl viologen
2-hydroxyglutarate + oxidized benzyl viologen
show the reaction diagram
2-oxoglutarate + reduced methyl viologen
2-hydroxyglutarate + oxidized methyl viologen
show the reaction diagram
2-oxononanoate + reduced benzyl viologen
2-hydroxynonanoate + oxidized benzyl viologen
show the reaction diagram
-
-
-
0
?
2-oxononanoate + reduced methyl viologen
2-hydroxynonanoate + oxidized methyl viologen
show the reaction diagram
-
-
-
0
?
3-fluoropyruvate + reduced benzyl viologen
3-fluoro-2-hydroxypropionate + oxidized benzyl viologen
show the reaction diagram
3-fluoropyruvate + reduced methyl viologen
3-fluoro-2-hydroxypropionate + oxidized methyl viologen
show the reaction diagram
5-benzyloxyindolylpyruvate + reduced benzyl viologen
3-(5-benzyloxyindolyl)-2-hydroxypropionate + oxidized benzyl viologen
show the reaction diagram
-
-
-
0
?
5-benzyloxyindolylpyruvate + reduced methyl viologen
3-(5-benzyloxyindolyl)-2-hydroxypropionate + oxidized methyl viologen
show the reaction diagram
-
-
-
0
?
6-phospho-D-gluconate + oxidized anthraquinone-2,6-disulfonate
6-phospho-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
6-phospho-D-gluconate + oxidized benzyl viologen
6-phospho-D-arabino-hex-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
6-phospho-D-gluconate + oxidized carboxamido-methyl viologen
6-phospho-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
a (2R)-hydroxy-carboxylate + acceptor
a 2-oxo-carboxylate + reduced acceptor
show the reaction diagram
chloropyruvic acid + reduced 1,1'-carbamoyl methyl viologen
D-(S)-chlorolactate + oxidized 1,1'-carbamoyl methyl viologen
show the reaction diagram
-
stereospecific reaction
-
0
?
D-galactonate + oxidized anthraquinone-2,6-disulfonate
D-lyxo-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
D-galactonate + oxidized benzyl viologen
D-lyxo-hex-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
D-galactonate + oxidized carboxamido-methyl viologen
D-lyxo-hex-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
D-glucarate + oxidized anthraquinone-2,6-disulfonate
2-oxo-D-glucarate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
D-glucarate + oxidized benzyl viologen
2-oxo-D-glucarate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
D-glucarate + oxidized carboxamido-methyl viologen
2-oxo-D-glucarate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
D-gluconate + oxidized 1,1'-carbamoyl methyl viologen
? + reduced 1,1'-carbamoyl methyl viologen
show the reaction diagram
-
anaerobic conditions
-
0
r
D-gluconate + oxidized anthraquinone-2,6-disulfonate
D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
D-gluconate + oxidized benzyl viologen
D-arabino-hex-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
D-gluconate + oxidized carboxamido-methyl viologen
D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
D-glucose 6-phosphate + oxidized 1,1'-carbamoyl methyl viologen
? + reduced 1,1'-carbamoyl methyl viologen
show the reaction diagram
-
anaerobic conditions
-
0
r
D-gulonate + oxidized anthraquinone-2,6-disulfonate
D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
D-gulonate + oxidized benzyl viologen
D-arabino-hex-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
D-gulonate + oxidized carboxamido-methyl viologen
D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
D-lactate + oxidized 1,1'-carbamoyl methyl viologen
pyruvate + reduced 1,1'-carbamoyl methyl viologen
show the reaction diagram
-
anaerobic conditions
-
0
r
D-lactate + oxidized anthraquinone-2,6-disulfonate
pyruvate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
D-lactate + oxidized benzyl viologen
pyruvate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
D-lactate + oxidized carboxamido-methyl viologen
pyruvate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
D-ribonate + oxidized anthraquinone-2,6-disulfonate
D-erythro-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
D-ribonate + oxidized benzyl viologen
D-erythro-pent-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
D-ribonate + oxidized carboxamido-methyl viologen
D-erythro-pent-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
D-xylonate + oxidized anthraquinone-2,6-disulfonate
D-threo-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
D-xylonate + oxidized benzyl viologen
D-threo-pent-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
D-xylonate + oxidized carboxamido-methyl viologen
D-threo-pent-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
dimethylsulfoxide + oxidized antraquinone-2,6-disulfonate
dimethylsulfide + reduced antraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
galactarate + oxidized anthraquinone-2,6-disulfonate
2-oxogalactarate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
galactarate + oxidized benzyl viologen
2-oxogalactarate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
galactarate + oxidized carboxamido-methyl viologen
2-oxogalactarate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
indolylpyruvate + reduced benzyl viologen
2-hydroxy-3-indolylpropionate + oxidized benzyl viologen
show the reaction diagram
indolylpyruvate + reduced methyl viologen
2-hydroxy-3-indolylpropionate + oxidized methyl viologen
show the reaction diagram
L-arabinonate + oxidized anthraquinone-2,6-disulfonate
L-erythro-pent-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
L-arabinonate + oxidized benzyl viologen
L-erythro-pent-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
L-arabinonate + oxidized carboxamido-methyl viologen
L-erythro-pent-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
L-arabinuronate + oxidized anthraquinone-2,6-disulfonate
? + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
L-arabinuronate + oxidized benzyl viologen
? + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
L-arabinuronate + oxidized carboxamido-methyl viologen
? + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
L-mannonate + oxidized anthraquinone-2,6-disulfonate
L-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
L-mannonate + oxidized benzyl viologen
L-arabino-hex-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
L-mannonate + oxidized carboxamido-methyl viologen
L-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
lactate + oxidized acceptor
pyruvate + reduced acceptor
show the reaction diagram
-
-
-
0
r
lactobionate + oxidized anthraquinone-2,6-disulfonate
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate
show the reaction diagram
-
-
-
0
r
lactobionate + oxidized benzyl viologen
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced benzyl viologen
show the reaction diagram
-
-
-
0
r
lactobionate + oxidized carboxamido-methyl viologen
4-O-(beta-D-galactopyranosido)-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen
show the reaction diagram
-
-
-
0
r
mandelate + oxidized acceptor
oxo(phenyl)acetic acid + reduced acceptor
show the reaction diagram
-
-
-
0
r
N-acetylneuraminate + oxidized 1,1'-carbamoyl methyl viologen
? + reduced 1,1'-carbamoyl methyl viologen
show the reaction diagram
-
anaerobic conditions
-
0
r
pantolactone + oxidized acceptor
dehydropantolactone + reduced acceptor
show the reaction diagram
-
-
-
0
r
phenylglyoxylate + reduced benzyl viologen
(R)-mandelic acid
show the reaction diagram
phenylglyoxylate + reduced methyl viologen
(R)-mandelic acid
show the reaction diagram
phenylpyruvate + H2
(2R)-phenyllactate
show the reaction diagram
-
-
-
0
r
phenylpyruvate + reduced 1,1'-carbamoyl methyl viologen
phenyllactate + oxidized 1,1'-carbamoyl methyl viologen
show the reaction diagram
-
anaerobic conditions
-
0
r
phenylpyruvate + reduced benzyl viologen
(2R)-phenyllactate + oxidized benzyl viologen
show the reaction diagram
-
-
-
0
r
phenylpyruvate + reduced benzyl viologen
2-hydroxy-3-phenylpropionate + oxidized benzyl viologen
show the reaction diagram
phenylpyruvate + reduced benzyl viologen
phenyllactate + oxidized benzyl viologen
show the reaction diagram
-
anaerobic conditions
-
0
r
phenylpyruvate + reduced carbamoylmethyl viologen
(2R)-phenyllactate + oxidized carbamoylmethyl viologen
show the reaction diagram
phenylpyruvate + reduced cobalt sepulchrate
(2R)-phenyllactate + oxidized cobalt sepulchrate
show the reaction diagram
-
-
-
0
r
phenylpyruvate + reduced indigocarmine
(2R)-phenyllactate + oxidized indigocarmine
show the reaction diagram
-
-
-
0
r
phenylpyruvate + reduced kresyl violet
(2R)-phenyllactate + oxidized kresyl violet
show the reaction diagram
-
-
-
0
r
phenylpyruvate + reduced meldolablue
(2R)-phenyllactate + oxidized meldolablue
show the reaction diagram
-
-
-
0
r
phenylpyruvate + reduced methyl viologen
2-hydroxy-3-phenylpropionate + oxidized methyl viologen
show the reaction diagram
phenylpyruvate + reduced methylene blue
(2R)-phenyllactate + oxidized methylene blue
show the reaction diagram
-
-
-
0
r
phenylpyruvate + reduced phenosafranine
(2R)-phenyllactate + oxidized phenosafranine
show the reaction diagram
-
-
-
0
r
phenylpyruvate + reduced safranine TH
(2R)-phenyllactate + oxidized safranine TH
show the reaction diagram
-
-
-
0
r
pyruvate + reduced benzyl viologen
lactate + oxidized benzyl viologen
show the reaction diagram
pyruvate + reduced methyl viologen
lactate + oxidized methyl viologen
show the reaction diagram
additional information
?
-