1.1.3.46: 4-hydroxymandelate oxidase

This is an abbreviated version!
For detailed information about 4-hydroxymandelate oxidase, go to the full flat file.

Word Map on EC 1.1.3.46

Reaction

(S)-4-hydroxymandelate
+
O2
=
2-(4-hydroxyphenyl)-2-oxoacetate
+
H2O2

Synonyms

4HmO, fegC, HmO, hydroxymandelate oxidase, L-4-hydroxymandelate oxidase, p-hydroxymandelate oxidase, Sco3228

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.46 4-hydroxymandelate oxidase

Natural Substrates Products

Natural Substrates Products on EC 1.1.3.46 - 4-hydroxymandelate oxidase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate + O2
2-(4-hydroxyphenyl)-2-oxoacetate + H2O2
show the reaction diagram
(S)-3,5-dihydroxymandelate + O2
2-(3,5-dihydroxyphenyl)-2-oxoacetate + H2O2
show the reaction diagram
-
the enzyme is involed in the biosynthesis of (S)-4-hydroxyphenylglycine and (S)-3,5-dihydroxyphenylglycine, two non-proteinogenic amino acids occurring in the vancomycin group of antibiotics
-
-
?
(S)-4-hydroxymandelate + O2
2-(4-hydroxyphenyl)-2-oxoacetate + H2O2
show the reaction diagram