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1.1.3.46: 4-hydroxymandelate oxidase

This is an abbreviated version!
For detailed information about 4-hydroxymandelate oxidase, go to the full flat file.

Word Map on EC 1.1.3.46

Reaction

(S)-4-hydroxymandelate
+
O2
=
2-(4-hydroxyphenyl)-2-oxoacetate
+
H2O2

Synonyms

4HmO, fegC, HmO, hydroxymandelate oxidase, L-4-hydroxymandelate oxidase, p-hydroxymandelate oxidase, Sco3228

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.46 4-hydroxymandelate oxidase

Reference

Reference on EC 1.1.3.46 - 4-hydroxymandelate oxidase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Müller, U.; van Assema, F.; Gunsior, M.; Orf, S.; Kremer, S.; Schipper, D.; Wagemans, A.; Townsend, C.A.; Sonke, T.; Bovenberg, R.; Wubbolts, M.
Metabolic engineering of the E. coli L-phenylalanine pathway for the production of D-phenylglycine (D-Phg)
Metab. Eng.
8
196-208
2006
Streptomyces coelicolor, Amycolatopsis orientalis (O52791), Amycolatopsis orientalis
Manually annotated by BRENDA team
Hubbard, B.K.; Thomas, M.G.; Walsh, C.T.
Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics
Chem. Biol.
7
931-942
2000
Amycolatopsis orientalis (G4V4S8), Amycolatopsis orientalis
Manually annotated by BRENDA team
Li, T.L.; Choroba, O.W.; Charles, E.H.; Sandercock, A.M.; Williams, D.H.; Spencer, J.B.
Characterisation of a hydroxymandelate oxidase involved in the biosynthesis of two unusual amino acids occurring in the vancomycin group of antibiotics
Chem. Commun. (Camb. )
21
1752-1753
2001
Amycolatopsis orientalis (G4V4S8)
Manually annotated by BRENDA team
Liu, S.P.; Liu, R.X.; El-Rotail, A.A.; Ding, Z.Y.; Gu, Z.H.; Zhang, L.; Shi, G.Y.
Heterologous pathway for the production of L-phenylglycine from glucose by E. coli
J. Biotechnol.
186C
91-97
2014
Amycolatopsis orientalis, Streptomyces coelicolor, Streptomyces coelicolor CGMCC 4.1092, Amycolatopsis orientalis ATCC 19795
Manually annotated by BRENDA team
Diez, V.; Loznik, M.; Taylor, S.; Winn, M.; Rattray, N.J.; Podmore, H.; Micklefield, J.; Goodacre, R.; Medema, M.H.; Mueller, U.; Bovenberg, R.; Janssen, D.B.; Takano, E.
Functional exchangeability of oxidase and dehydrogenase reactions in the biosynthesis of hydroxyphenylglycine, a nonribosomal peptide building block
ACS Synth. Biol.
4
796-807
2015
Streptomyces coelicolor (Q9Z4X8), Streptomyces coelicolor
Manually annotated by BRENDA team
Gonsior, M.; Muehlenweg, A.; Tietzmann, M.; Rausch, S.; Poch, A.; Suessmuth, R.D.
Biosynthesis of the peptide antibiotic feglymycin by a linear nonribosomal peptide synthetase mechanism
ChemBioChem
16
2610-2614
2015
Streptomyces sp. (A0A0P0KG57), Streptomyces sp. DSM11171 (A0A0P0KG57)
Manually annotated by BRENDA team
Chen, Y.; Wu, P.; Ko, L.; Kao, T.; Liu, L.; Zhang, Y.; Yuan, J.
High-yielding protocatechuic acid synthesis from l -tyrosine in Escherichia coli
ACS Sust. Chem. Eng.
8
14949-14954
2020
Streptomyces coelicolor
-
Manually annotated by BRENDA team
Yeh, H.; Lin, K.; Lyu, S.; Li, Y.; Huang, C.; Wang, Y.; Shih, H.; Hsu, N.; Wu, C.; Li, T.
Biochemical and structural explorations of a-hydroxyacid oxidases reveal a four-electron oxidative decarboxylation reaction
Acta Crystallogr. Sect. D
75
733-742
2019
Amycolatopsis orientalis (O52792)
Manually annotated by BRENDA team
Lyu, S.; Lin, K.; Yeh, H.; Li, Y.; Huang, C.; Wang, Y.; Shih, H.; Hsu, N.; Wu, C.; Li, T.
The flavin mononucleotide cofactor in alpha-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate-oxidation level
Acta Crystallogr. Sect. D
75
918-929
2019
Amycolatopsis orientalis (O52792)
Manually annotated by BRENDA team