1.1.1.412: 2-alkyl-3-oxoalkanoate reductase

This is an abbreviated version, for detailed information about 2-alkyl-3-oxoalkanoate reductase, go to the full flat file.

Reaction

a (2R,3S)-2-alkyl-3-hydroxyalkanoate
+
NADP+
=
an (R)-2-alkyl-3-oxoalkanoate
+
NADPH
+
H+

Synonyms

2-alkyl-3-ketoalkanoic acid reductase, oleD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.412 2-alkyl-3-oxoalkanoate reductase

KM Value

KM Value on EC 1.1.1.412 - 2-alkyl-3-oxoalkanoate reductase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.181
(2R,3S)-2-hexyl-3-hydroxydecanoic acid
-
at pH 8.0 and 25°C
0.161
(2R/2S)-2-hexyl-3-oxodecanoic acid
-
at pH 8.0 and 25°C
-
0.024
NADP+
-
at pH 8.0 and 25°C
0.026
NADPH
-
at pH 8.0 and 25°C
0.031
syn-2-decyl-3-hydroxytetradecanoic acid
-
at pH 8.0 and 25°C
-
0.202
syn-2-hexyl-3-hydroxydecanoic acid
-
at pH 8.0 and 25°C
-
0.214
syn-2-octyl-3-hydroxydodecanoic acid
-
at pH 8.0 and 25°C
-