1.1.1.412: 2-alkyl-3-oxoalkanoate reductase

This is an abbreviated version!
For detailed information about 2-alkyl-3-oxoalkanoate reductase, go to the full flat file.

Reaction

a (2R,3S)-2-alkyl-3-hydroxyalkanoate
+
NADP+
=
an (R)-2-alkyl-3-oxoalkanoate
+
NADPH
+
H+

Synonyms

2-alkyl-3-ketoalkanoic acid reductase, oleD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.412 2-alkyl-3-oxoalkanoate reductase

Substrates Products

Substrates Products on EC 1.1.1.412 - 2-alkyl-3-oxoalkanoate reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP+
(R)-2-alkyl-3-oxoalkanoate + NADPH + H+
show the reaction diagram
(2R,3S)-2-hexyl-3-hydroxydecanoic acid + NADPH + H+
?
show the reaction diagram
(2R/2S)-2-hexyl-3-oxodecanoic acid + NADPH + H+
?
show the reaction diagram
(R)-2-alkyl-3-oxoalkanoate + NADPH + H+
(2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP+
show the reaction diagram
syn-2-decyl-3-hydroxytetradecanoic acid + NADPH + H+
?
show the reaction diagram
100% activity
-
-
?
syn-2-hexyl-3-hydroxydecanoic acid + NADPH + H+
?
show the reaction diagram
15% activity compared to syn-2-decyl-3-hydroxytetradecanoic acid
-
-
?
syn-2-octyl-3-hydroxydodecanoic acid + NADPH + H+
?
show the reaction diagram
20% activity compared to syn-2-decyl-3-hydroxytetradecanoic acid
-
-
?
additional information
?
-