1.1.1.412: 2-alkyl-3-oxoalkanoate reductase

This is an abbreviated version, for detailed information about 2-alkyl-3-oxoalkanoate reductase, go to the full flat file.

Reaction

a (2R,3S)-2-alkyl-3-hydroxyalkanoate
+
NADP+
=
an (R)-2-alkyl-3-oxoalkanoate
+
NADPH
+
H+

Synonyms

2-alkyl-3-ketoalkanoic acid reductase, oleD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.412 2-alkyl-3-oxoalkanoate reductase

Reference

Reference on EC 1.1.1.412 - 2-alkyl-3-oxoalkanoate reductase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bonnett, S.A.; Papireddy, K.; Higgins, S.; del Cardayre, S.; Reynolds, K.A.
Functional characterization of an NADPH dependent 2-alkyl-3-ketoalkanoic acid reductase involved in olefin biosynthesis in Stenotrophomonas maltophilia
Biochemistry
50
9633-9640
2011
Stenotrophomonas maltophilia (B2FI29), Stenotrophomonas maltophilia, Stenotrophomonas maltophilia K279a (B2FI29)
Manually annotated by BRENDA team
Kancharla, P.; Bonnett, S.A.; Reynolds, K.A.
Stenotrophomonas maltophilia OleC-catalyzed ATP-dependent formation of long-chain Z-olefins from 2-alkyl-3-hydroxyalkanoic acids
ChemBioChem
17
1426-1429
2016
Stenotrophomonas maltophilia (B2FI29), Stenotrophomonas maltophilia K279a (B2FI29)
Manually annotated by BRENDA team