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Information on EC 2.4.2.8 - hypoxanthine phosphoribosyltransferase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.8 hypoxanthine phosphoribosyltransferase
IUBMB Comments
Guanine and purine-6-thiol can replace hypoxanthine.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
hprt, hgprt, hypoxanthine-guanine phosphoribosyltransferase, hprt1, hypoxanthine phosphoribosyltransferase, hypoxanthine-guanine phosphoribosyl transferase, hypoxanthine phosphoribosyl transferase, hypoxanthine guanine phosphoribosyltransferase, hgprtase, guanine phosphoribosyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
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