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2.7.1.B26: aminoglycoside 3'-phosphotransferase

This is an abbreviated version!
For detailed information about aminoglycoside 3'-phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.B26

Reaction

GTP
+
gentamicin JI-20A
=
GDP
+
gentamicin JI-20A 3'-phosphate

Synonyms

aminoglycoside 3'-phosphotransferase VIII, APH(3'), APH-3'-IIIa, Aph3, APHVIII, biosynthetic aminoglycoside 3'-phosphotransferase, GnTI

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.B26 aminoglycoside 3'-phosphotransferase

Reference

Reference on EC 2.7.1.B26 - aminoglycoside 3'-phosphotransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
McKay, G.A.; Roestamadji, J.; Mobashery, S.; Wright, G.D.
Recognition of aminoglycoside antibiotics by enterococcal-staphylococcal aminoglycoside 3'-phosphotransferase type IIIa: role of substrate amino groups
Antimicrob. Agents Chemother.
40
2648-2650
1996
Enterococcus faecium (E9LMR8)
Manually annotated by BRENDA team
Shao, L.; Chen, J.; Wang, C.; Li, J.A.; Tang, Y.; Chen, D.; Liu, W.
Characterization of a key aminoglycoside phosphotransferase in gentamicin biosynthesis
Bioorg. Med. Chem. Lett.
23
1438-1441
2013
Micromonospora echinospora (Q6QVT6), Micromonospora echinospora ATCC 15835 (Q6QVT6)
Manually annotated by BRENDA team
Thompson, P.R.; Hughes, D.W.; Wright, G.R.
Mechanism of aminoglycoside 3'-phosphotransferase type IIIa: His188 is not a phosphate-accepting residue
Chem. Biol.
3
747-755
1996
Enterococcus faecium (E9LMR8)
Manually annotated by BRENDA team
Lin, H.; Cliften, P.F.; Dutcher, S.K.
MAPINS, a highly efficient detection method that identifies insertional mutations and complex DNA rearrangements
Plant Physiol.
178
1436-1447
2018
Streptomyces rimosus
Manually annotated by BRENDA team