2.7.1.56: 1-phosphofructokinase

This is an abbreviated version!
For detailed information about 1-phosphofructokinase, go to the full flat file.

Word Map on EC 2.7.1.56

2.7.1.56

fructose-specific

fructose-grown

entner-doudoroff

hpr

phosphoenolpyruvate-dependent

1,6-bisphosphate

embden-meyerhof

phosphoenolpyruvate:fructose

iifru

embden-meyerhof-parnas

ribokinase

capsulata

Reaction

Synonyms

1-PFK, 1PFK, D-fructose-1-phosphate kinase, FruC, fructose 1-phosphate kinase, fructose-1-phosphate kinase, kinase, 1-phosphofructo- (phosphorylating), PFK, PFK-1, PFK1, PFK2, pfkB, phosphofructokinase 1, phosphofructokinase-1

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.56 1-phosphofructokinase

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Results	in table
2	Activating Compound
2524	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
1	Cofactor
2	Expression
5	General Information
4	General Stability
42	Inhibitors
2	kcat/KM [mM/s]
3	Ki Value [mM]
25	KM Value [mM]
1	Localization
45	Metals/Ions
15	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
51	Organism
5	Pathway
2	PDB ID
10	pH Optimum
5	pH Range
1	pI Value
1	Protein Variants
13	Purification (Commentary)
1	Reaction
1	Reaction Type
25	Reference
9	Source Tissue
8	Specific Activity [micromol/min/mg]
9	Storage Stability
57	Substrates and Products (Substrate)
8	Subunits
26	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 2.7.1.56 - 1-phosphofructokinase

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ATP + D-fructose 1-phosphate

ADP + D-fructose 1,6-bisphosphate

30 entries

ATP + D-fructose 6-phosphate

ADP + ?

2 entries

CTP + D-fructose 1-phosphate

CDP + D-fructose 1,6-bisphosphate

4 entries

GTP + D-fructose 1-phosphate

GDP + D-fructose 1,6-bisphosphate

7 entries

ITP + D-fructose 1-phosphate

IDP + D-fructose 1,6-bisphosphate

5 entries

TTP + D-fructose 1-phosphate

TDP + D-fructose 1,6-bisphosphate

3 entries

UTP + D-fructose 1-phosphate

UDP + D-fructose 1,6-bisphosphate

5 entries

additional information

Homo sapiens

important role for PFK-1 in normal proton pump function. Loss of a-subunit/PFK-1 interaction is likely to decrease the stability of the metabolon formed by various H+ATPase subunits (notably E and a) and glycolytic components (aldolase and PFK-1)

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