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2.7.1.39: homoserine kinase

This is an abbreviated version!
For detailed information about homoserine kinase, go to the full flat file.

Word Map on EC 2.7.1.39

Reaction

ATP
+
L-homoserine
=
ADP
+
O-phospho-L-homoserine

Synonyms

CglThrB, CThrB, DMR1, homoserine kinase, homoserine kinase (phosphorylating), HSK, kinase (phosphorylating), homoserine, kinase, homoserine (phosphorylating), Thr1, Thr1p, ThrB

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.39 homoserine kinase

Substrates Products

Substrates Products on EC 2.7.1.39 - homoserine kinase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + 4-hydroxynorvaline
ADP + 4-phospho-L-norvaline
show the reaction diagram
-
0.3% of the activity with L-homoserine
-
-
?
ATP + D-homoserine
ADP + O-phospho-D-homoserine
show the reaction diagram
-
32% of the turnover number with L-homoserine
-
-
?
ATP + L-2-amino-1,4-butanediol
ADP + ?
show the reaction diagram
-
7.9% of the turnover number with L-homoserine
-
-
?
ATP + L-2-amino-5-hydroxyvalerate
ADP + L-2-amino-5-phosphovalerate
show the reaction diagram
-
9.9% of the turnover number with L-homoserine
-
-
?
ATP + L-aspartate 4-semialdehyde
?
show the reaction diagram
ATP + L-homoserine
ADP + O-phospho-L-homoserine
show the reaction diagram
ATP + L-homoserine ethyl ester
ADP + O-phospho-L-homoserine ethyl ester
show the reaction diagram
-
74% of the turnover number with L-homoserine
-
-
?
ATP + L-homoserine isopropyl ester
ADP + O-phospho-L-homoserine isopropyl ester
show the reaction diagram
-
74% of the turnover number with L-homoserine
-
-
?
ATP + L-homoserine isubutyl ester
ADP + O-phospho-L-homoserine isobutyl ester
show the reaction diagram
-
84% of the turnover number with L-homoserine
-
-
?
ATP + L-homoserine methyl ester
ADP + O-phospho-L-homoserine methyl ester
show the reaction diagram
-
80% of the turnover number with L-homoserine
-
-
?
ATP + L-homoserine n-butyl ester
ADP + O-phospho-L-homoserine n-butyl ester
show the reaction diagram
-
160% of the turnover number with L-homoserine
-
-
?
ATP + L-homoserine n-propyl ester
ADP + O-phospho-L-homoserine n-propyl ester
show the reaction diagram
-
76% of the turnover number with L-homoserine
-
-
?
L-homoserine + ATP
O-phospho-L-homoserine + ADP
show the reaction diagram
-
-
-
-
?
additional information
?
-
-
enzyme has inherent ATPase activity
-
-
?