2.6.1.86: 2-amino-4-deoxychorismate synthase
This is an abbreviated version!
For detailed information about 2-amino-4-deoxychorismate synthase, go to the full flat file.
Word Map on EC 2.6.1.86
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2.6.1.86
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anthranilate
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ammonia
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phenazine
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synthases
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amidotransferase
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enzyme-bound
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venezuelae
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aminodeoxychorismate
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chorismate-utilizing
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biotechnology
- 2.6.1.86
- anthranilate
- ammonia
- phenazine
- synthases
-
amidotransferase
-
enzyme-bound
- venezuelae
-
aminodeoxychorismate
-
chorismate-utilizing
- biotechnology
Reaction
Synonyms
2-amino-2-deoxyisochorismate (ADIC) synthase, 2-amino-2-deoxyisochorismate synthase, 2-amino-2desoxyisochorismate synthase, ADCS, ADIC synthase, aminodeoxyisochorismate synthase, PabA, PhzE, SgcD
ECTree
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Engineering
Engineering on EC 2.6.1.86 - 2-amino-4-deoxychorismate synthase
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K274A/L277R/D299E/N303H/I306L/F334Y/C391G
mutant displaying anthranilate synthase activity, the kcat/Kchoris value for anthranilate formation is 25% of the wild-type aminodeoxychorismate synthase value for 4-amino-4-deoxychorismate production
N213V/L214P/K274A/L277R/D299E/N303H/F334Y/P363N/I367L/C391G/G425A
mutant displaying anthranilate synthase activity, is able to produce both 2-amino-2-deoxyisochorismate and anthranilate
N213V/L214P/R259S/K274A/L277R/N303H/F334Y/S366T/C391G/G254A
mutant displaying anthranilate synthase activity, is able to produce both 2-amino-2-deoxyisochorismate and anthranilate