2.6.1.86: 2-amino-4-deoxychorismate synthase

This is an abbreviated version!
For detailed information about 2-amino-4-deoxychorismate synthase, go to the full flat file.

Word Map on EC 2.6.1.86

2.6.1.86

anthranilate

ammonia

phenazine

synthases

amidotransferase

enzyme-bound

venezuelae

aminodeoxychorismate

chorismate-utilizing

biotechnology

Reaction

Synonyms

2-amino-2-deoxyisochorismate (ADIC) synthase, 2-amino-2-deoxyisochorismate synthase, 2-amino-2desoxyisochorismate synthase, ADCS, ADIC synthase, aminodeoxyisochorismate synthase, PabA, PhzE, SgcD

ECTree

2 Transferases

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.1.86 2-amino-4-deoxychorismate synthase

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Results	in table
128	AA Sequence
1	Application
1	CAS Registry Number
3	Cloned(Commentary)
1	Crystallization (Commentary)
3	Inhibitors
2	KM Value [mM]
3	Metals/Ions
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
7	Organism
6	Pathway
1	pH Optimum
1	pH Range
3	Protein Variants
3	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
8	Substrates and Products (Substrate)
4	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.6.1.86 - 2-amino-4-deoxychorismate synthase

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chorismate + L-glutamine

(2S)-2-amino-4-deoxychorismate + L-glutamate

Streptomyces globisporus

the net conversion of chorismate to 3-enolpyruvoylanthranilate by the tandem action of SgcD and SgcG establishes a new branching point in chorismate metabolism leading to synthesis of C-1027, an enediyne antitumor antibiotic

682589

additional information

Pseudomonas fluorescens

the enzyme participates in the biosynthesis of phenazine, a precursor for several compounds with antibiotic activity

680341