2.6.1.86: 2-amino-4-deoxychorismate synthase

This is an abbreviated version!
For detailed information about 2-amino-4-deoxychorismate synthase, go to the full flat file.

Word Map on EC 2.6.1.86

2.6.1.86

anthranilate

ammonia

phenazine

synthases

amidotransferase

enzyme-bound

venezuelae

aminodeoxychorismate

chorismate-utilizing

biotechnology

Reaction

Synonyms

2-amino-2-deoxyisochorismate (ADIC) synthase, 2-amino-2-deoxyisochorismate synthase, 2-amino-2desoxyisochorismate synthase, ADCS, ADIC synthase, aminodeoxyisochorismate synthase, PabA, PhzE, SgcD

ECTree

2 Transferases

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.1.86 2-amino-4-deoxychorismate synthase

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Results	in table
128	AA Sequence
1	Application
1	CAS Registry Number
3	Cloned(Commentary)
1	Crystallization (Commentary)
3	Inhibitors
2	KM Value [mM]
3	Metals/Ions
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
7	Organism
6	Pathway
1	pH Optimum
1	pH Range
3	Protein Variants
3	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
8	Substrates and Products (Substrate)
4	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Turnover Number [1/s]

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Reference on EC 2.6.1.86 - 2-amino-4-deoxychorismate synthase

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33303

Morollo, A.A.; Bauerle, R.

Characterization of composite aminodeoxyisochorismate synthase and aminodeoxyisochorismate lyase activities of anthranilate synthase

Proc. Natl. Acad. Sci. USA

9983-9987

1993

Salmonella enterica subsp. enterica serovar Typhimurium

8234345

680341

McDonald, M.; Mavrodi, D.V.; Thomashow, L.S.; Floss, H.G.

Phenazine biosynthesis in Pseudomonas fluorescens: branchpoint from the primary shikimate biosynthetic pathway and role of phenazine-1,6-dicarboxylic acid

J. Am. Chem. Soc.

123

9459-9460

2001

Pseudomonas fluorescens

11562236

682589

Van Lanen, S.G.; Lin, S.; Shen, B.

Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism

Proc. Natl. Acad. Sci. USA

105

494-499

2008

Streptomyces globisporus

18182490

724464

Culbertson, J.E.; Toney, M.D.

Expression and characterization of PhzE from P. aeruginosa PAO1: aminodeoxyisochorismate synthase involved in pyocyanin and phenazine-1-carboxylate production

Biochim. Biophys. Acta

1834

240-246

2013

Pseudomonas aeruginosa (G3XCK6), Pseudomonas aeruginosa

23099261

725425

Li, Q.A.; Mavrodi, D.V.; Thomashow, L.S.; Roessle, M.; Blankenfeldt, W.

Ligand binding induces an ammonia channel in 2-amino-2-desoxyisochorismate (ADIC) synthase PhzE

J. Biol. Chem.

286

18213-18221

2011

Burkholderia lata, Burkholderia lata 383

21454481

737705

Culbertson, J.E.; Chung, D.h.; Ziebart, K.T.; Espiritu, E.; Toney, M.D.

Conversion of aminodeoxychorismate synthase into anthranilate synthase with Janus mutations: mechanism of pyruvate elimination catalyzed by chorismate enzymes

Biochemistry

2372-2384

2015

Escherichia coli (P00903)

25710100