2.5.1.90: all-trans-octaprenyl-diphosphate synthase

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For detailed information about all-trans-octaprenyl-diphosphate synthase, go to the full flat file.

Reaction

Synonyms

C40-OPP, cel, gbs1789, IspB, long-chain C40 octaprenyl diphosphate synthase, long-chain trans-prenyltransferase, octaprenyl diphosphate synthase, octaprenyl pyrophosphate, octaprenyl pyrophosphate synthase, octaprenyl-diphosphate synthase, Opp, OPP synthase, OPP synthetase, OPPs, trans-prenyltransferase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.90 all-trans-octaprenyl-diphosphate synthase

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Results	in table
2	Activating Compound
3381	AA Sequence
11	Cloned(Commentary)
5	Crystallization (Commentary)
14	General Information
3	IC50 Value
5	Inhibitors
1	Ki Value [mM]
48	KM Value [mM]
4	Metals/Ions
1	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
27	Organism
5	Pathway
8	PDB ID
1	pH Optimum
48	Protein Variants
9	Purification (Commentary)
3	Reaction
26	Reference
2	Source Tissue
4	Specific Activity [micromol/min/mg]
37	Substrates and Products (Substrate)
5	Subunits
30	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Stability [°C]
29	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.5.1.90 - all-trans-octaprenyl-diphosphate synthase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate

5 diphosphate + all-trans-octaprenyl diphosphate

7 entries

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate

5 diphosphate + all-trans-octaprenyl diphosphate

Escherichia coli

-

-

759417

-

-

?

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate

5 diphosphate + all-trans-octaprenyl diphosphate

Escherichia coli

P0AD57

-

739617, 758792, 758934

-

-

?

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate

5 diphosphate + all-trans-octaprenyl diphosphate

Escherichia coli

-

-

758934

-

-

?

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate

5 diphosphate + all-trans-octaprenyl diphosphate

Escherichia coli

P0AD57

the enzyme catalyzes the successive condensation of farnesyl diphosphate with five isopentenyl pyrophosphate molecules to form trans-C40-octaprenyl diphosphate

737369

-

-

?

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate

5 diphosphate + all-trans-octaprenyl diphosphate

Escherichia coli K12

P0AD57

-

758934

-

-

?

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate

5 diphosphate + all-trans-octaprenyl diphosphate

Thermotoga maritima

Q9X1M1

the polymer all-trans C40-octaprenyl pyrophosphate forms the side chain of ubiquinone that is involved in electron transport system to produce ATP

747162

-

-

?

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate

5 diphosphate + all-trans-octaprenyl diphosphate

Thermotoga maritima DSM 3109

Q9X1M1

the polymer all-trans C40-octaprenyl pyrophosphate forms the side chain of ubiquinone that is involved in electron transport system to produce ATP

747162

-

-

?