2.5.1.65: O-phosphoserine sulfhydrylase

This is an abbreviated version!
For detailed information about O-phosphoserine sulfhydrylase, go to the full flat file.

Reaction

Synonyms

APE1586, ApOPSS, CysK2, CysM, O-acetyl-L-serine sulfhydrylase, O-acetylserine sulfhydrylase, O-phospho-L-serine sulfhydrylase, O-phospho-L-serine-dependent S-sulfocysteine synthase, O-phosphoserine S-sulfocysteine synthase, O-phosphoserine specific cysteine synthase, O-phosphoserine(thiol)-lyase, OASS, OPSS, Rv1336, S-sulfocysteine synthase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.65 O-phosphoserine sulfhydrylase

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Results	in table
1	Activating Compound
70	AA Sequence
1	CAS Registry Number
11	Cloned(Commentary)
12	Cofactor
8	Crystallization (Commentary)
8	General Information
23	Inhibitors
12	kcat/KM [mM/s]
29	KM Value [mM]
3	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
20	Organism
9	Pathway
30	PDB ID
7	pH Optimum
4	pH Stability
23	Protein Variants
9	Purification (Commentary)
10	Reaction
2	Reaction Type
15	Reference
7	Specific Activity [micromol/min/mg]
1	Storage Stability
59	Substrates and Products (Substrate)
8	Subunits
32	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
3	Temperature Stability [°C]
22	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 2.5.1.65 - O-phosphoserine sulfhydrylase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

1

Aeropyrum pernix

-

mutant R297A, substrate O-phospho-L-serine

659728

23

Aeropyrum pernix

Q9YBL2

pH 7.5, 80°C

722990

245

Aeropyrum pernix

-

wild-type enzyme, substrate O-phospho-L-serine

659728

50.9

Aeropyrum pernix

-

pH 6.7, 60°C, O-acetyl-L-serine sulfhydrylation

637385

53.1

Aeropyrum pernix

-

mutant R297A, substrate O-acetyl-L-serine

659728

54.5

Aeropyrum pernix

-

60°C, O-acetyl-L-serine sulfhydrylation reaction, recombinant OASS

655576

72

Aeropyrum pernix

-

wild-type enzyme, substrate O-acetyl-L-serine

659728