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2.5.1.21: squalene synthase

This is an abbreviated version!
For detailed information about squalene synthase, go to the full flat file.

Word Map on EC 2.5.1.21

Reaction

2 (2E,6E)-farnesyl diphosphate +

NAD(P)H
+
H+
=
squalene
 + 2 diphosphate +
NAD(P)+

Synonyms

BbSS, BSS, CrSQS, dt-ySQase, Erg9, EtSS, farnesyl-diphosphate farnesyltransferase, farnesyl-diphosphate:farnesyldiphosphate farnesyltransferase, farnesyldiphosphate farnesyltransferase 1, farnesyldiphosphate:farnesyldiphosphate farnesyltransferase, farnesyltransferase, FDFT1, hSQS, presqualene synthase, presqualene-diphosphate synthase, SgSQS, SQase, SQS, SQS1, SQS2, squalene synthase, squalene synthase 1, squalene synthase 2, squalene synthetase, SS1, SSase, SSN, synthase, squalene, TkSQS1, TkSQS2

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.21 squalene synthase

Storage Stability

Storage Stability on EC 2.5.1.21 - squalene synthase

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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-70°C, stable
-
-80°C, 25 mM sodium phosphate (pH 7.4, containing 20 mM NaCl, 2 mM dithiothreitol, 1 mM EDTA, 40% glycerol, 10% methanol, 1 mM phenylmethylsulfonyl fluoride, 0.01 mM leupeptin, 0.001 mM pepstatin), extended periods of time, no loss of activity
-
-80°C, stable for at least 6 months
Thermosynechococcus vestitus
-