2.4.2.17: ATP phosphoribosyltransferase

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For detailed information about ATP phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

1-(5-phospho-D-ribosyl)-ATP:pyrophosphate phospho-alpha-D-ribosyltransferase, adenosine 5'-triphosphate phosphoribosyltransferase, adenosine triphosphate phosphoribosyltransferase, adenosine-triphosphate phosphoribosyltransferase, ATP phosphoribosyl transferase, ATP phosphoribosyl transferase complex, ATP phosphoribosyltransferase, ATP-phosphoribosyl transferase, ATP-phosphoribosyltransferase, ATP-PRT, ATP-PRT1, ATP-PRT2, ATP-PRTase, ATPPRT, HisG, HisGL, N-1-(5'-phosphoribosyl)-ATP transferase, phosphoribosyl ATP synthetase, phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase, phosphoribosyl-ATP pyrophosphorylase, phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase, phosphoribosyladenosine triphosphate pyrophosphorylase, phosphoribosyladenosine triphosphate synthetase, phosphoribosyltransferase, adenosine triphosphate

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.17 ATP phosphoribosyltransferase

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Results	in table
3	Activating Compound
36759	AA Sequence
3	Application
1	CAS Registry Number
20	Cloned(Commentary)
12	Crystallization (Commentary)
2	Expression
1	General Information
5	General Stability
14	IC50 Value
101	Inhibitors
18	kcat/KM [mM/s]
28	Ki Value [mM]
51	KM Value [mM]
1	Localization
19	Metals/Ions
18	Molecular Weight [Da]
55	Natural Substrates/ Products (Substrates)
253	Organism
6	Pathway
100	PDB ID
11	pH Optimum
1	pH Range
1	pH Stability
32	Protein Variants
25	Purification (Commentary)
8	Reaction
1	Reaction Type
49	Reference
13	Source Tissue
9	Specific Activity [micromol/min/mg]
5	Storage Stability
83	Substrates and Products (Substrate)
31	Subunits
77	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
1	Temperature Range [°C]
8	Temperature Stability [°C]
29	Turnover Number [1/s]

Expression

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Expression on EC 2.4.2.17 - ATP phosphoribosyltransferase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

forced histidine exposure (through injection or feeding) significantly inhibits the enzyme mRNA levels at higher concentrations

Nilaparvata lugens

-

758630

histidine exposure significantly increases enzyme expression levels at lower concentrations (feeding only)

Nilaparvata lugens

-

758630