2.4.1.80: ceramide glucosyltransferase
This is an abbreviated version!
For detailed information about ceramide glucosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.80
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2.4.1.80
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glucosylceramide
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glycosphingolipids
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sphingolipids
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gangliosides
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gm3
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sphingoid
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galactosylceramide
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d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol
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gaucher
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d-pdmp
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n-butyldeoxynojirimycin
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nb-dnj
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1-phenyl-2-decanoylamino-3-morpholino-1-propanol
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galcers
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medicine
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udp-galactose:ceramide
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glucocerebroside
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cgalt
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laccer
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conduritol
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pharmacology
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molecular biology
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drug development
- 2.4.1.80
- glucosylceramide
- glycosphingolipids
- sphingolipids
- gangliosides
- gm3
-
sphingoid
- galactosylceramide
- d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol
- gaucher
-
d-pdmp
- n-butyldeoxynojirimycin
-
nb-dnj
- 1-phenyl-2-decanoylamino-3-morpholino-1-propanol
-
galcers
- medicine
-
udp-galactose:ceramide
- glucocerebroside
- cgalt
-
laccer
-
conduritol
- pharmacology
- molecular biology
- drug development
Reaction
Synonyms
ceramide glucosyltransferase, ceramide glycosyltransferase, ceramide:UDP-glucose glucosyltransferase, ceramide:UDPGlc glucosyltransferase, cerebroside synthase, CGT, cgt-1, cgt-2, cgt-3, GCS, GCS1, GlcCer synthase, GlcCerS, GlcT, GlcT-1, glucosylceramide synthase, glucosyltransferase, uridine diphosphoglucose-ceramide, GluT, UDP glucose-ceramide glucosyltransferase, UDP-Glc:ceramide glucosyltransferase, UDP-glucoase:ceramide glucosyltransferase, UDP-glucose ceramide glucosyltransferase, UDP-glucose ceramide glycosyltransferase, UDP-glucose: ceramide glucosyltransferase, UDP-glucose:ceramide glucosyltransferase, Ugcg, uridine diphosphate (UDP)-glucose:N-acylsphingosine D-glucosyltransferase, uridine diphosphoglucose-ceramide glucosyltransferase
ECTree
2.4.1.80 ceramide glucosyltransferaseAdvanced search results
results (
results (Activating Compound
Activating Compound on EC 2.4.1.80 - ceramide glucosyltransferase
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ACTIVATING COMPOUND 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
c-Fos
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activity of glucosylceramide synthase is around 5fold higher in presence of high c-Fos levels, induced by nerve growth factor NGF, addition of c-Fos mRNA ASO, which specifically blocks c-Fos expression abolished the induction of glucosylceramide synthase by NGF
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dioleoyl phosphatidylcholine
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or other exogenous phospholipid, required for activity
L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol
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L-PDMP treatment induces a 2.4 increase in glucosylceramide
detergent
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optimal activity obtained with a mixture of Cutsum and Triton X-100 (2:1)
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detergent
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activity is reduced by most of the detergents tested, only CHAPS and CHAPSO at concentration of 1% w/v stimulate
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HSP70
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dog heat shock protein 70 increases production of glucosylceramide to 207%
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HSP70
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dog heat shock protein 70 increases production of glucosylceramide to 149%
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NADH
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omission in assay containing Golgi vesicles leads to loss of about 90% activity
