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2.4.1.206: lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

This is an abbreviated version!
For detailed information about lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.206

Reaction

UDP-N-acetyl-alpha-D-glucosamine
+
beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
=
UDP
 +
N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Synonyms

acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-lactosylceramide beta-, beta1,3 N-acetylglucosaminyltransferase GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide synthase, beta1,3-N-acetylglucosaminyltransferase-2, beta1-3-N-acetylglucosaminyltransferase, beta3Gn-T2, beta3Gn-T5, beta3GnT5, GlcNAc transferase, LA2 synthase, LacCer(beta1,3)N-acetylglucosaminyltransferase, lactosylceramide beta-acetylglucosaminyltransferase, lactosylceramide: N-acetylglucosaminyltransferase, lactosylceramide:N-acetylglucosaminyltransferase, lactotriaosylceramide synthase, Lc2Cer-Glc-NAc-Tr, Lc3 synthase, Lc3 synthase/bGn-T5, UDP-GlcNAc:lactosylceramide beta1,3-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.206 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

Cloned

Cloned on EC 2.4.1.206 - lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DNA and amino acid sequence determination, functional expression in Spodoptera frugiperda Sf9 cells via baculovirus infection
DNA sequence determination and analysis
DNA sequence determination, functional expression in Spodoptera frugiperda Sf9 cells via baculovirus infection
expressed in COS-7 cells
-
expression in Escherichia coli, overexpression of beta3GnT5 in MNK-45 cells and AGS cells, transfection with lipofectamine
-
expression in Nawalma cells, membrane-bound
gene B3gnt5, chromosome 16 B1
-
partial sequence, not a full length clone, DNA sequence determination
soluble expression as FLAG-tagged protein in Spodoptera frugiperda Sf21 cells via baculovirus infection