2.4.1.206: lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase
This is an abbreviated version!
For detailed information about lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, go to the full flat file.
Word Map on EC 2.4.1.206
Reaction
Synonyms
acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-lactosylceramide beta-, beta1,3 N-acetylglucosaminyltransferase GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide synthase, beta1,3-N-acetylglucosaminyltransferase-2, beta1-3-N-acetylglucosaminyltransferase, beta3Gn-T2, beta3Gn-T5, beta3GnT5, GlcNAc transferase, LA2 synthase, LacCer(beta1,3)N-acetylglucosaminyltransferase, lactosylceramide beta-acetylglucosaminyltransferase, lactosylceramide: N-acetylglucosaminyltransferase, lactosylceramide:N-acetylglucosaminyltransferase, lactotriaosylceramide synthase, Lc2Cer-Glc-NAc-Tr, Lc3 synthase, Lc3 synthase/bGn-T5, UDP-GlcNAc:lactosylceramide beta1,3-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase
ECTree
2.4.1.206 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferaseAdvanced search results
results (
results (Source Tissue
Source Tissue on EC 2.4.1.206 - lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
the enzyme is expressedin two distinct phases during the zebrafish embryogenesis. The early phase extends from late blastulation to the completion of epiboly, during which the expression occurs in the superficial layer of the embryos. The second phase of expression starts during mid-segmentation and persists until day 3, during which the expression occurs prominently in the developing lens. Hedgehog signaling is required for the Lc3 synthase expression in embryonic lens
-
Daoy and D341 Med, cultured both in vitro and as xenografts in nude mice
additional information
distinct cellular layers: Purkinje cell layer, molecular cell layer, granule cell layer + white matter
-
distinct cellular layers: Purkinje cell layer, molecular cell layer, granule cell layer + white matter
the enzyme is expressed in two distinct phases during the zebrafish embryogenesis. The early phase extends from late blastulation to the completion of epiboly, during which the expression occurs in the superficial layer of the embryos. The second phase of expression starts during mid-segmentation and persists until day 3, during which the expression occurs prominently in the developing lens
-
E17 fetus, both head and body show strong expression of Lc3 synthase in wild-type (Wt/Wt) and heterozygous (Wt/KO) mice
-
E17 fetus, both head and body show strong expression of Lc3 synthase in wild-type (Wt/Wt) and heterozygous (Wt/KO) mice
-
additional information
transcript content and activity in diverse tumour cell lines, overview, nearly undetectable content in leukemic cell lines
additional information
-
transcript content and activity in diverse tumour cell lines, overview, nearly undetectable content in leukemic cell lines
additional information
-
enzyme levels in brain regions during pre- and postnatal brain development
additional information
enzyme levels in brain regions during pre- and postnatal brain development
additional information
-
retinoic acid activates the enzyme and leads to developmental malformations of the embryos, overview
